Show of the Month July 2012
Show of
the Month July 13 2012
What You Eat Can Prevent Arsenic Overload
Caffeine Boosts Power for Elderly Muscles
Light Weights Are Just as Good for Building Muscle, Getting Stronger
Building Muscle Without Heavy Weights
Tannic acid inhibited norovirus
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What You Eat Can Prevent Arsenic Overload
ScienceDaily (June 29, 2012) — Millions of people worldwide are exposed to arsenic from contaminated water, and we are all exposed to arsenic via the food we eat. New research published in BioMed Central's open access journal Nutrition Journal has demonstrated that people who ate more dietary vitamin B12 and animal protein had lower levels of arsenic (measured by deposition in toenails). Total dietary fat, animal fat, vegetable fat and saturated fat were also all associated with lower levels of arsenic, while omega 3 fatty acids, such as those found in fish oil, were associated with increased arsenic.---Long term exposure to high levels of arsenic is known to cause skin lesions, cancer and cardiovascular disease, and also affects fetal development. Even low concentrations of arsenic are potentially dangerous. Arsenic is found in some water supplies, but more people are exposed via their diet. Staples such as rice contain arsenic, especially the toxic inorganic forms, while fish, although high in total arsenic, contains organic forms which are thought to be less toxic.[U1]---Inside the body arsenic is methylated to aid excretion in urine but arsenic also has an affinity for keratin and can be deposited in hair and nails as they grow. Consequently levels of arsenic preserved in nails or hair can be used as a biomarker for arsenic exposure over periods of months to years.---Researchers from Dartmouth College and the Geisel School of Medicine at Dartmouth looked at the levels of arsenic in toenails of residents of New Hampshire who all use private groundwater wells as their household water source.---Results of the study showed that arsenic in nails was positively associated with both alcohol and omega 3 fatty acids, however, lower levels of arsenic were found for people who ate greater amounts of vegetable and animal fat. Prof Kathy Cottingham, who directed the study, explained, "While there may be a direct interaction between fats and arsenic preventing absorption or binding to keratin in nails, the results may simply reflect dietary preference, with people who eat a diet rich in fats not eating foods high in arsenic, such as rice."---Joann Gruber, who led the study, noted that, "Humans can be very efficient at removing arsenic from the body. Improved methylation reduces the amount of inorganic arsenic circulating in the body. Surprisingly, we didn't see a reduction in toenail arsenic with other dietary factors known to be necessary for arsenic methylation such as folic acid. This may be because the population we sampled had adequate amounts of these factors in their diet."---The authors are currently working on similar studies in children, through the Children's Environmental Health and Disease Prevention Center at Dartmouth.--Story Source-The above story is reprinted from materials provided by BioMed Central. ---Journal Reference-Joann F Gruber, Margaret R Karagas, Diane Gilbert-Diamond, Pamela J Bagley, M Scot Zens, Vicki Sayarath, Tracy Punshon, J Steven Morris and Kathryn L Cottingham. Associations between toenail arsenic concentration and dietary factors in a New Hampshire population. Nutrition Journal, 2012; (in press) [link]---
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Caffeine Boosts Power for Elderly Muscles
Caffeine helps muscles to produce more force, new study shows.---ScienceDaily (June 29, 2012) — A new study to be presented at the Society for Experimental Biology meeting on 30th June has shown that caffeine boosts power in older muscles, suggesting the stimulant could aid elderly people to maintain their strength, reducing the incidence of falls and injuries.---For adults in their prime, caffeine helps muscles to produce more force. But as we age, our muscles naturally change and become weaker.--Sports scientists at Coventry University looked for the first time at whether these age-related changes in muscle would alter the effect of caffeine. They found that caffeine continued to enhance muscle performance in two different muscles from mice, although it was less effective in older muscles.---Jason Tallis, the study's primary author, said: "Despite a reduced effect in the elderly, caffeine may still provide performance-enhancing benefits."-For adults in their prime, caffeine helps muscles to produce more force. But as we age, our muscles naturally change and become weaker. So, sports scientists at Coventry University looked for the first time at whether these age-related changes in muscle would alter the effect of caffeine.--Caffeine's effect was smallest for juvenile muscles, suggesting caffeine may not have an enhancing effect in developing muscles.--The decline in muscle strength that occurs as we age contributes to injuries and reduces quality of life. The process is not well understood, but it is clear that preserving muscle tone is key.---Tallis said: "With the importance of maintaining a physically active lifestyle to preserve health and functional capacity, the performance-enhancing benefit of caffeine could prove beneficial in the aging population."---The researchers isolated muscles from mice ranging in age from juvenile to elderly, then tested their performance before and after caffeine treatment. They looked at two different skeletal muscles, which are the muscles we can control voluntarily. The first was the diaphragm, a core muscle used for respiration; the second was a leg muscle called the extensor digitorum longus (EDL), used for locomotion.---Story Source-The above story is reprinted from materials provided by Society for Experimental Biology, via EurekAlert!, a service of AAAS.
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Light Weights Are Just as Good for Building Muscle, Getting Stronger, Researchers Find
Lifting less weight more times is just as effective at building muscle as training with heavy weights, a finding by McMaster researchers that turns conventional wisdom on its head. ---ScienceDaily (Apr. 30, 2012) — Lifting less weight more times is just as effective at building muscle as training with heavy weights, a finding by McMaster researchers that turns conventional wisdom on its head.---The key to muscle gain, say the researchers, is working to the point of fatigue.---"We found that loads that were quite heavy and comparatively light were equally effective at inducing muscle growth and promoting strength," says Cam Mitchell, one of the lead authors of the study and a PhD candidate in the Department of Kinesiology.---The research, published in the Journal of Applied Physiology, challenges the widely accepted dogma that training with heavy weights -- which can be lifted only six to 12 times before fatigue -- is the best avenue to muscle growth.--"Many older adults can have joint problems which would prevent them training with heavy loads," says Mitchell. "This study shows that they have the option of training with lighter and less intimidating loads and can still receive the benefits."---For the study, a series of experiments were conducted on healthy, young male volunteers to measure how their leg muscles reacted to different forms of resistance training over a period of 10 weeks.--The researchers first determined the maximum weight each subject could lift one time in a knee extension. Each subject was assigned to a different training program for each leg.--In all, three different programs were used in combinations that required the volunteers to complete sets of as many repetitions as possible with their assigned loads -- typically eight to 12 times per set at the heaviest weights and 25-30 times at the lowest weights.---The three programs used in the combinations were:
- one set at 80% of the maximum load
- three sets at 80% of the maximum
- three sets at 30% of the maximum
After 10 weeks of training, three times per week, the heavy and light groups that lifted three sets saw significant gains in muscle volume -- as measured by MRI -- with no difference among the groups. Still, the group that used heavier weights for three sets developed a bit more strength.---The group that trained for a single set showed approximately half the increase in muscle size seen in both the heavy and light groups.---"The complexity of current resistance training guidelines may deter some people from resistance training and therefore from receiving the associated health benefits," says Stuart Phillips, a professor in the Department of Kinesiology and supervisor of the study. "Our study provides evidence for a simpler paradigm, where a much broader range of loads including quite light loads can induce muscle growth, provided it is lifted to the point where it is difficult to maintain good form."--Story Source--The above story is reprinted from materials provided by McMaster University, via Newswise. --Journal Reference---C. J. Mitchell, T. A. Churchward-Venne, D. D. W. West, N. A. Burd, L. Breen, S. K. Baker, S. M. Phillips. Resistance exercise load does not determine training-mediated hypertrophic gains in young men. Journal of Applied Physiology, 2012; DOI: 10.1152/japplphysiol.00307.2012
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Building Muscle Without Heavy Weights
ScienceDaily (Apr. 26, 2012) — Weight training at a lower intensity but with more repetitions may be as effective for building muscle as lifting heavy weights says a new opinion piece in Applied Physiology, Nutrition, and Metabolism.--"The perspective provided in this review highlights that other resistance protocols, beyond the often discussed high-intensity training, can be effective in stimulating a muscle building response that may translate into bigger muscles after resistance training," says lead author Nicholas Burd. "These findings have important implications from a public health standpoint because skeletal muscle mass is a large contributor to daily energy expenditure and it assists in weight management. Additionally, skeletal muscle mass, because of its overall size, is the primary site of blood sugar disposal and thus will likely play a role in reducing the risk for development of type II diabetes."---The authors from McMaster University conducted a series of experiments that manipulated various resistance exercise variables (e.g., intensity, volume, and muscle time under tension). They found that high-intensity muscle contractions derived from lifting heavy loads were not the only drivers of exercise-induced muscle development. In resistance-trained young men a lower workout intensity and a higher volume of repetitions of resistance exercise, performed until failure, was equally effective in stimulating muscle proteins as a heavy workout intensity at lower repetition rates. An additional benefit of the low-intensity workout is that the higher repetitions required to achieve fatigue will also be beneficial for sustaining the muscle building response for days.---Story Source---The above story is reprinted from materials provided by Canadian Science Publishing (NRC Research Press), via EurekAlert!, a service of AAAS.
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Tannic acid inhibited norovirus binding to HBGA receptors, a study of 50 Chinese medicinal herbs.
Bioorg Med Chem. 2012 Feb 15;20(4):1616-23
Authors: Zhang XF, Dai YC, Zhong W, Tan M, Lv ZP, Zhou YC, Jiang X
Abstract
Noroviruses (NoVs) are the leading cause of viral acute gastroenteritis affecting people of all ages worldwide. The disease is difficult to control due to its widespread nature and lack of an antiviral or vaccine. NoV infection relies on the interaction of the viruses with histo-blood group antigens (HBGAs) as host receptors. Here we investigated inhibition effects of Chinese medicinal herbs against NoVs binding to HBGAs for potential antivirals against NoVs. Blocking assays was performed using the NoV protrusion (P) protein as NoV surrogate and saliva as HBGAs. Among 50 clinically effective Chinese medicinal herbs against gastroenteritis diseases, two herbs were found highly effective. Chinese Gall blocked NoV P dimer binding to type A saliva at IC(50)=5.35 μg/ml and to B saliva at IC(50)=21.7 μg/ml. Similarly, Pomegranate blocked binding of NoV P dimer to type A saliva at IC(50)=15.59 μg/ml and B saliva at IC(50)=66.67 μg/ml. Literature data on preliminary biochemistry analysis showed that tannic acid is a common composition in the extracts of the two herbs, so we speculate that it might be the effective compound and further studies using commercially available, highly purified tannic acid confirmed the tannic acid as a strong inhibitor in the binding of NoV P protein to both A and B saliva (IC(50)≈0.1 μM). In addition, we tested different forms of hydrolysable tannins with different alkyl esters, including gallic acid, ethyl gallate, lauryl gallate, octyl gallate and propyl gallate. However, none of these tannins-derivatives revealed detectable inhibiting activities. Our data suggested that tannic acid is a promising candidate antiviral against NoVs.---PMID: 22285570 [PubMed - indexed for MEDLINE]*********************************************************************
Tea, nettle, wood, berries, Chinese galls. Oak wood is very rich in tannic acid. When wine is kept in oak kegs some tannic acid will migrate into the wine. High levels of tannic acid are found in some plant galls. These are formed by plants when they are infected by certain insects. These insects pierce the plant leaves and when the egg hatches out into a larva the plant produces a gall which surrounds the larva.---- Tannic acid has anti-bacterial, anti-enzymatic and astringent properties. Tannic acid has constringing action upon mucous tissues such as tongue and inside of mouth. The ingestion of tannic acid caused constipation and can be used to treat diarrhoea (in the absence of fever or inflammation). The anti-oxidant and anti-mutagenic properties of tannic acid are beneficial.--- Externally, tannic acid is used to treat ulcers, toothache and wounds
[U1]This is another one of those oxymorons—this form of this is dangerious and this form of this is OK -----this is all nonsensical---this is marketing to get people to eat left over and to induce stupidity to convince you that eating shit is ok
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Newer vitamin D tests often inaccurate, study shows-Faster,
less expensive tests may overestimate vitamin D deficiency
Low Testosterone Appears To Increase Long-Term Risk Of Death
Sleep Loss Dramatically Lowers Testosterone in Healthy Young Men
World’s First GM Babies BornWorld’s First GM Babies Born
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Newer vitamin D tests often inaccurate, study shows-Faster, less expensive tests may overestimate vitamin D deficiency
June 25, 2012 —
Two new lab tests to measure blood levels of vitamin D are inaccurate more than 40% of the time, according to a new study.-Researchers say newer tests tend to overestimate the number of people who are deficient in vitamin D, a problem that could cause patients to be anxious about their health and may lead to over-treatment.[U1]-The study, which was presented at ENDO 2012, the annual meeting of the endocrine society in Houston, is adding to concerns felt in many laboratories and hospitals around the country that the results of vitamin D tests, which have become some of the most frequently ordered blood tests in medicine, are widely unreliable.-What's more, experts say, vitamin D testing is often ordered under circumstances where there's little solid scientific evidence to support its use.--"It's a huge problem," says researcher Earle W. Holmes, PhD, a pathologist at Loyola University Stritch School of Medicine, in Chicago.--Experts who were not involved in the research agree.--"The biggest problem is that they're not even consistent," says Ravinder J. Singh, PhD, director of the Mayo Clinic's Endocrinology Laboratory in Rochester, Minn. "At least if they were consistent, you could say, values are half or double, compared to other tests. You can never have confidence" in the results, he tells WebMD.--The new tests, made by Abbott and Siemens, were approved by the FDA last fall.---They're part of a wave of faster, less expensive tests designed to help laboratories keep up with a boom in demand for vitamin D testing.--Abbott took issue with the study results, pointing to a company-funded study that showed their vitamin D test delivered results that are accurate and comparable to a widely used reference method.---Siemens also defended their test, saying they are reviewing the validity of the study.
Questions Persist About Vitamin D Testing
It's not the first time questions have been raised about the accuracy of vitamin D tests, however.--In 2009, Quest Diagnostics, one of the largest medical laboratories in the --At the time, industry analysts called it the largest patient recall of a laboratory test in recent memory. The company offered free retesting.--Vitamin D, the "sunshine vitamin," plays a well-known and important role in bone health. But in recent years, a raft of research has suggested that low vitamin D may be a factor in a host of other health conditions, including depression, diabetes, cancer, heart disease, and autoimmune diseases.--As a result, doctors have increasingly ordered the test to check vitamin D levels in their patients. The number of vitamin D tests has increased six- to 10-fold over the last decade at some hospitals and laboratories. Industry analysts say the vitamin D tests are now one of the most frequently ordered lab tests in medicine.--"The rate of testing has gone up over the last five to 10 years in an almost exponential fashion," says Naveed Sattar, MD, PhD, a professor of metabolic medicine at the University of Glasgow, in Scotland. Sattar wrote a recent editorial on vitamin D testing for The Lancet, but he was not involved in the research. Sattar says vitamin D testing has raced ahead of the science, leaving doctors in the dark about how to handle abnormal results. ---"Many results are coming back in patients who appear otherwise healthy, but they appear to have low levels. And the physicians don't know what to do, whether they should supplement or not," Sattar says.---Sattar says there's little evidence to suggest that supplementing vitamin D is useful, except perhaps as a treatment for bone loss. The recommended dietary allowances for vitamin D in adults up to 70 years old is 600 International Units (IU) and 800 IU for adults over 70.---While the NIH states a tolerable upper intake level of 4,000 IU, Sattar says that back in the 1950s, when vitamin D was first added to foods, the fortification process wasn't closely monitored and some infants developed dangerously high blood levels of calcium as a result.--Beyond physical harm, however, Sattar says telling someone they are deficient in vitamin D could cause needless anxiety.---"If it were me, I'd be scratching my head. Am I doing something wrong? Should I go spend more time in the sun? Should I be eating certain foods? So that's a hazard by itself," he says.--Someone who looks deficient in D might be prescribed supplements and further testing, increasing costs."I think this does need to be looked at carefully," Sattar says.
Study Details---Holmes and his team wanted to see how well the new tests performed compared to an older, more expensive, and more time-consuming reference method. They were hoping the hospital could switch to one of the newer tests to save money and time.--They ran blood samples from 163 patients on all three tests. The Abbott Architect test was outside an acceptable margin of error -- meaning that the results were either 25% too high or too low, about 40% of the time. The Siemens Centaur2 test was either too high or too low in 48% of samples. In many cases, the newer tests showed that patients were deficient in vitamin D when the reference test indicated they were not.---The new tests use blood proteins called antibodies that bind to vitamin D. They're faster because they look for vitamin D in samples of whole blood.--In the older, reference method, vitamin D is separated from the blood and measured. The older test can also measure two different forms of vitamin D: Vitamin D2, which is the form of the vitamin found in fortified foods and in the kind of high-potency supplements that doctors prescribe to treat patients; and Vitamin D3, the form of the vitamin that the body makes naturally after skin is exposed to sunlight. The newer test can't distinguish between the two different types of D.---Holmes says vitamin D2 seems to confuse the tests.--He says the tests' inability to accurately measure that form of the vitamin means that doctors can't tell if their patients are getting any benefit from it or if they're taking their supplements as directed.--"You can't tell if you're making a difference for the patients," Holmes says.--In absolute numbers, the reference test showed 33 patients out of 163 were deficient in vitamin D, while the Abbott test showed 45 people were vitamin D deficient, and the Siemens test pointed to deficiency in 71 patients.--Current guidelines by the Institute of Medicine state a vitamin D level of at least 20 nanograms per milliliter (ng/ml) in the blood as adequate for bone health and overall health. However, other experts, including Holmes, feel that a normal level is 30 ng/ml or higher.---Manufacturers Respond--In a statement issued in response to the study, Abbott, the company that makes the Architect test, says the results of the current study depend on the use of a reference test that is "a very hands-on, labor intensive, manual procedure for which there currently is no standard protocol or calibration method. As a result, this leads to variability of results from lab to lab."--"In current studies ... as well as in recent proficiency surveys, the ARCHITECT Vitamin D test showed excellent precision and reproducibility of results from lab to lab," the statement reads.---Siemens is checking the study's accuracy: "Siemens Healthcare Diagnostics is committed to delivering high-quality solutions and services to our customers that enable health care professionals to accurately diagnose, treat, and monitor patients. We are closely reviewing the validity of the claims made in this report along with the design of the methods and analysis used to develop them."---The wholesale price of the newer tests is estimated to cost around $20 to $25, although patients and insurance companies may be charged more. That's about half the cost of the older reference test, experts said, which wholesaled for about $50 a test.--This study was presented at a medical conference. The findings should be considered preliminary, as they have not yet undergone the "peer review" process, in which outside experts scrutinize the data prior to publication in a medical journal.--SOURCES: Annual meeting of The Endocrine Society, Houston, June 23-26, 2012.Sattar, N. The Lancet, January 2012.National Institutes of Health, Office of Dietary Supplements: "Dietary Supplement Fact Sheet: Vitamin D."Earle W. Holmes, PhD, professor of pathology and molecular pharmacology, Stritch School of Medicine, Loyola University, Chicago.Ravinder J. Singh, PhD, director, Endocrinology Laboratory, Mayo Clinic, Rochester, Minn.Naveed Sattar, MD, PhD, professor of metabolic medicine, University of Glasgow, Glasgow, Scotland, U.K.
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Low Testosterone Appears To Increase Long-Term Risk Of Death
ScienceDaily (June 17, 2008) — Men may not live as long if they have low testosterone, regardless of their age, according to a new study.--The new study, from Germany, adds to the scientific evidence linking deficiency of this sex hormone with increased death from all causes over time--so-called "all-cause mortality."---The results should serve as a warning for men with low testosterone to have a healthier lifestyle, including weight control, regular exercise and a healthy diet, said lead author Robin Haring, a PhD student from Ernst-Moritz-Arndt University of Greifswald, Institute for Community Medicine.---"It is very possible that lifestyle determines levels of testosterone," he said. ---In the study, Haring and co-workers looked at death from any cause in nearly 2,000 men aged 20 to 79 years who were living in northeast Germany and who participated in the Study of Health in Pomerania (SHIP). Follow-up averaged 7 years. At the beginning of the study, 5 percent of these men had low blood testosterone levels, defined as the lower end of the normal range for young adult men. The men with low testosterone were older, more obese, and had a greater prevalence of diabetes and high blood pressure, compared with men who had higher testosterone levels, Haring said.---Men with low testosterone levels had more than 2.5 times greater risk of dying during the next 10 years compared to men with higher testosterone, the study found. This difference was not explained by age, smoking, alcohol intake, level of physical activity, or increased waist circumference (a risk factor for diabetes and heart disease), Haring said.----In cause-specific death analyses, low testosterone predicted increased risk of death due to cardiovascular disease and cancer but not death of any other single cause.----DPC Biermann, Bad Nauheim, Germany, provided the testosterone reagent, and Novo Nordisc provided partial funding for this analysis.---Detailed results will be presented at The Endocrine Society's 90th Annual Meeting in San Francisco.---Story Source--The above story is reprinted from materials provided by The Endocrine Society, via EurekAlert!, a service of AAAS.
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Sleep Loss Dramatically Lowers Testosterone in Healthy Young Men
ScienceDaily (May 31, 2011) — Cutting back on sleep drastically reduces a healthy young man's testosterone levels, according to a study published in the June 1 issue of the Journal of the American Medical Association (JAMA).-Eve Van Cauter, PhD, professor in medicine and director of the study, found that men who slept less than five hours a night for one week in a laboratory had significantly lower levels of testosterone than when they had a full night's sleep. Low testosterone has a host of negative consequences for young men, and not just in sexual behavior and reproduction. It is critical in building strength and muscle mass, and bone density.-"Low testosterone levels are associated with reduced well being and vigor, which may also occur as a consequence of sleep loss" said Van Cauter.----At least 15% of the adult working population in the US gets less than 5 hours of sleep a night, and suffers many adverse health effects because of it. This study found that skipping sleep reduces a young man's testosterone levels by the same amount as aging 10 to 15 years. "As research progresses, low sleep duration and poor sleep quality are increasingly recognized as endocrine disruptors," Van Cauter said. The ten young men in the study were recruited from around the University of Chicago campus. They passed a rigorous battery of tests to screen for endocrine or psychiatric disorders and sleep problems. They were an average of 24 years old, lean and in good health. For the study, they spent three nights in the laboratory sleeping for up to ten hours, and then eight nights sleeping less than five hours. Their blood was sampled every 15 to 30 minutes for 24 hours during the last day of the ten-hour sleep phase and the last day of the five-hour sleep phase. The effects of sleep loss on testosterone levels were apparent after just one week of short sleep. Five hours of sleep decreased their testosterone levels by 10% to 15%. The young men had the lowest testosterone levels in the afternoons on their sleep restricted days, between 2 pm and 10 pm. The young men also self-reported their mood and vigor levels throughout the study. They reported a decline in their sense of well-being as their blood testosterone levels declined. Their mood and vigor fell more every day as the sleep restriction part of the study progressed. Testosterone levels in men decline by 1% to 2% a year as they age. Testosterone deficiency is associated with low energy, reduced libido, poor concentration, and fatigue. The National Heart, Lung, and Blood Institute funded this study. Additional funding came from the National Institute of Diabetes and Digestive and Kidney Diseases, and the National Institutes of Health. Rachel Leproult, PhD, organized and supervised the experiment which took place in the University of Chicago Clinical Research Center.---Story Source-The above story is reprinted from materials provided by University of Chicago Medical Center, via EurekAlert!, a service of AAAS. --Journal Reference--R. Leproult, E. Van Cauter. Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men. JAMA: The Journal of the American Medical Association, 2011; 305 (21): 2173 DOI: 10.1001/jama.2011.710
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Declining Testosterone Levels in Men Not Part of Normal Aging
ScienceDaily (June 23, 2012) — A new study finds that a drop in testosterone levels over time is more likely to result from a man's behavioral and health changes than by aging. The study results will be presented June 25 at The Endocrine Society's 94th Annual Meeting in Houston.---"Declining testosterone levels are not an inevitable part of the aging process, as many people think," said study co-author Gary Wittert, MD, professor of medicine at the University of Adelaide in Adelaide, Australia. "Testosterone changes are largely explained by smoking behavior and changes in health status, particularly obesity and depression."--Many older men have low levels of the sex hormone testosterone, but the cause is not known. Few population-based studies have tracked changes in testosterone levels among the same men over time, as their study did, Wittert said.
In this study, supported by the National Health and Medical Research Council of Australia, the authors analyzed testosterone measurements in more than 1,500 men who had measurements taken at two clinic visits five years apart. All blood testosterone samples underwent testing at the same time for each time point, according to Wittert.---After the researchers excluded from the analysis any men who had abnormal lab values or who were taking medications or had medical conditions known to affect hormones, they included 1,382 men in the data analysis. Men ranged in age from 35 to 80 years, with an average age of 54.---On average, testosterone levels did not decline significantly over five years; rather, they decreased less than 1 percent each year, the authors reported. However, when the investigators analyzed the data by subgroups, they found that certain factors were linked to lower testosterone levels at five years than at the beginning of the study.---"Men who had declines in testosterone were more likely to be those who became obese, had stopped smoking or were depressed at either clinic visit," Wittert said. "While stopping smoking may be a cause of a slight decrease in testosterone, the benefit of quitting smoking is huge."---Past research has linked depression and low testosterone. This hormone is important for many bodily functions, including maintaining a healthy body composition, fertility and sex drive. "It is critical that doctors understand that declining testosterone levels are not a natural part of aging and that they are most likely due to health-related behaviors or health status itself," he said.---Unmarried men in the study had greater testosterone reductions than did married men. Wittert attributed this finding to past research showing that married men tend to be healthier and happier than unmarried men. "Also, regular sexual activity tends to increase testosterone," he explained.---The study findings were presented by Andre Araujo, PhD, who was a visiting professor at the University of Adelaide and is vice president of epidemiology at New England Research Institutes, Watertown, Mass.--Story Source-The above story is reprinted from materials provided by Endocrine Society, via Newswise.
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http://canadianawareness.org/2012/06/worlds-first-gm-babies-born/
The world’s first geneticallymodified humans have been created, it was revealed last night.---The disclosure that 30 healthy babies were born after a series of experiments in the United States provoked another furious debate about ethics.---So far, two of the babies have been tested and have been found to contain genes from three ‘parents’.---Fifteen of the children were born in the past three years as a result of one experimental programme at the Institute for Reproductive Medicine and Science of St Barnabas in New Jersey.--The babies were born to women who had problems conceiving. Extra genes from a female donor were inserted into their eggs before they were fertilised in an attempt to enable them to conceive.--Genetic fingerprint tests on two one-year- old children confirm that they have inherited DNA from three adults –two women and one man.---The fact that the children have inherited the extra genes and incorporated them into their ‘germline’ means that they will, in turn, be able to pass them on to their own offspring.--Altering the human germline – in effect tinkering with the very make-up of our species – is a technique shunned by the vast majority of the world’s scientists.---Geneticists fear that one day this method could be used to create new races of humans with extra, desired characteristics such as strength or high intelligence.[U2] Writing in the journal Human Reproduction, the researchers, led by fertility pioneer Professor Jacques Cohen, say that this ‘is the first case of human germline genetic modification resulting in normal healthy children’.--Some experts severely criticised the experiments. Lord Winston, of the Hammersmith Hospital in West London, told the BBC yesterday: ‘Regarding the treat-ment of the infertile, there is no evidence that this technique is worth doing . . . I am very surprised that it was even carried out at this stage. It would certainly not be allowed in Britain.’---John Smeaton, national director of the Society for the Protection of Unborn Children, said: ‘One has tremendous sympathy for couples who suffer infertility problems. But this seems to be a further illustration of the fact that the whole process of in vitro fertilisation as a means of conceiving babies leads to babies being regarded as objects on a production line.--‘It is a further and very worrying step down the wrong road for humanity.’ Professor Cohen and his colleagues diagnosed that the women were infertile because they had defects in tiny structures in their egg cells, called mitochondria.--They took eggs from donors and, using a fine needle, sucked some of the internal material – containing ‘healthy’ mitochondria – and injected it into eggs from the women wanting to conceive.-Because mitochondria contain genes, the babies resulting from the treatment have inherited DNA from both women. These genes can now be passed down the germline along the maternal line.--A spokesman for the Human Fertilisation and Embryology Authority (HFEA), which regulates ‘assisted reproduction’ technology in Britain, said that it would not license the technique here because it involved altering the germline.
Jacques Cohen is regarded as a brilliant but controversial scientist who has pushed the boundaries of assisted reproduction technologies. He developed a technique which allows infertile men to have their own children, by injecting sperm DNA straight into the egg in the lab. Prior to this, only infertile women were able to conceive using IVF. Last year, Professor Cohen said that his expertise would allow him to clone children –a prospect treated with horror by the mainstream scientific community. ‘It would be an afternoon’s work for one of my students,’ he said, adding that he had been approached by ‘at least three’ individuals wishing to create a cloned child, but had turned down their request
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[U1]Over-treatment??? Hahah more like Kidney stones-heart stones-lung stones---and the stones in the heart and lung could be a permenant reminder of listening to stupid ideas coming from people who do not know anything
[U2]I love this “ one day this method could be used to create a NEW RACE ---it’s called transhuman or Super soldier ---but we are being political here and this “ One day “ is about 20 years in the past ---in other words there Among us
Final frontier of climate policy - remake humans
Reverse Engineering Epilepsy's 'Miracle' Diet
Glucose Deprivation Activates Feedback Loop That Kills Cancer Cells
Drinking Coffee with Caffeine may Reduce the risk of Basal Cell Carcinoma
Moderate Coffee Consumption Offers Protection Against Heart Failure
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Final frontier of climate policy - remake humans
IF IT is so hard to change the climate to suit humans, why not alter humans to suit the changing climate, philosophers from Oxford and New York universities are asking.---They suggest humans could be modified to be smaller, dislike eating meat, have fewer children and be more willing to co-operate with social goals.[U1]--Behavioural changes might not be enough to prevent climate change even if they were widely adopted, and international agreements for measures such as emissions trading are proving elusive, say Matthew Liao of New York University and Anders Sandberg and Rebecca Roache of Oxford University.---So human engineering deserves serious consideration in the debate about how to solve climate change, they write in a coming paper for the academic journal Ethics, Policy & Environment.--A person's ecological footprint is directly correlated to size, because larger people eat more than lighter people, their cars need more fuel to carry them and they wear out shoes, carpets and furniture sooner than lighter people, the authors write. They suggest hormone treatments could be used to suppress child growth, or embryos could be selected for smaller size.--Reducing consumption of red meat could have significant environmental benefits, the paper says, citing estimates that as much as 51 per cent of the world's greenhouse gas emissions come from livestock farming. They say people who lack the motivation or willpower to give up eating meat could be helped by ''meat patches'' on their skin to deliver hormones to stimulate their immune system against common bovine proteins.--''Eating 'eco-unfriendly' food would induce unpleasant experiences,'' the authors say.[U2]--Better educated women have fewer children, so human engineering to improve cognition could reduce fertility as ''a positive side effect from the point of view of tackling climate change'', the paper argues.--Pharmacological treatments such as the ''love drug'' oxytocin could encourage people to act as a group and boost their appreciation of other life forms and nature, [U3]the authors say.--The paper has sparked a storm in the blogosphere. The environmentalist Bill McKibben tweeted that the authors had proposed ''the worst climate-change solutions of all time''. They have also been denounced as Nazis and ecofascists.--The authors are bemused but unrepentant. If people were willing to consider ''really dangerous'' geoengineering solutions such as using space mirrors to alter the Earth's solar reflectivity, human engineering should also be on the table, Dr Liao said.---''At least the human engineering solutions we have described rely on tried and tested technology, whose risks, at least at the individual level, are comparatively low and well known.''[U4]---The authors emphasise they are not advocating human engineering be adopted, only that it be considered. They also envisage it as a voluntary activity possibly supported by incentives such as tax breaks or sponsored healthcare, not something coerced or mandatory.---[U5]Dr Sandberg, of the Future of Humanity Institute at Oxford University, said the paper had inadvertently ''managed to press two hot buttons'' - climate change and ''messing with human nature''. He predicted the paper would mutate into a story that scientists were working on re-engineering people to be green and it would be adopted as ''yet another piece of evidence of the Big Conspiracy''.---This story was found at: http://www.smh.com.au/world/science/final-frontier-of-climate-policy--remake-humans-20120405-1wfo6.html
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Reverse Engineering Epilepsy's 'Miracle' Diet
ScienceDaily (May 23, 2012) — For decades, neurologists have known that a diet high in fat and extremely low in carbohydrates can reduce epileptic seizures that resist drug therapy. But until now, how the diet worked, and why, was a mystery.---Now, researchers at Dana-Farber Cancer Institute and Harvard Medical School have proposed an answer, linking resistance to seizures to a protein that modifies cellular metabolism in the brain. The research, to be published in the May 24th issue of the journal Neuron, may lead to the development of new treatments for epilepsy.--The research was led jointly by Nika Danial, HMS assistant professor of cell biology at Dana-Farber Cancer Institute, and Gary Yellen,professor of neurobiology at Harvard Medical School. The first author was Alfredo Giménez-Cassina, a research fellow in Danial's lab.---Epilepsy is a neurological disorder characterized by repeated seizures, an electrical storm in the brain that can manifest as convulsions, loss of motor control, or loss of consciousness. Some cases of epilepsy can be improved by a diet that drastically reduces sugar intake, triggering neurons to switch from their customary fuel of glucose to fat byproducts called ketone bodies. The so-called ketogenic diet, which mimics effects of starvation, was described more than 80 years ago and received renewed interest in the 1990s. Recent studies corroborate that it works, but shed little light on how.--"The connection between metabolism and epilepsy has been such a puzzle," said Yellen, who was introduced to the ketogenic diet through his wife, Elizabeth Thiele, HMS professor of neurology, who directs the Pediatric Epilepsy Program at MassGeneral Hospital for Children, but was not directly involved in the study. "I've met a lot of kids whose lives are completely changed by this diet," Yellen said. "It's amazingly effective, and it works for many kids for whom drugs don't work."---"We knew we needed to come at this link between metabolism and epilepsy from a new angle," said Danial, who had previously discovered a surprising double duty for a protein known for its role in apoptosis: The protein, BCL-2-associated Agonist of Cell Death, or BAD, also regulated glucose metabolism.--Giménez-Cassina further discovered that certain modifications in BAD switched metabolism in brain cells from glucose to ketone bodies. "It was then that we realized we had come upon a metabolic switch to do what the ketogenic diet does to the brain without any actual dietary therapy," said Gimenez-Cassina, who went on to show that these same BAD modifications protect against seizures in experimental models of epilepsy. Still, it wasn't clear exactly how.---Yellen suspected the solution involved potassium ion channels. While sodium and calcium ion channels tend to excite cells, including neurons, potassium channels tend to suppress cell electrical activity. His lab had previously linked ketone bodies to the activation of ATP-sensitive potassium (KATP) channels in neurons. Yellen had hypothesized that the ketogenic diet workedbecause ketone bodies provide neurons enough fuel for normal function, but when the electrical and energy storm of an epileptic seizure threatens, the activated KATP channels can shut the storm down. But the effects of diets are broad and complex, so it was impossible to say for sure---The effects that Danial's lab had discovered -- BAD's ability to alter metabolism and seizures -- offered a new avenue for studying the therapeutic effects of altered metabolism. Together, the researchers decided to investigate whether Danial's switch governed Yellen's pathway, and whether they could reverse engineer the seizure protection of a ketogenic diet.--They could. Working in genetically altered mice, the researchers modified the BAD protein to reduce glucose metabolism and increase ketone body metabolism in the brain. Seizures decreased, but the benefit was erased when they knocked out the KATP channel -- strong evidence that a BAD-KATP pathway conferred resistance to epileptic seizures. Further experiments suggested that it was indeed BAD's role in metabolism, not cell death that mattered. The findings make the BAD protein a promising target for new epilepsy drugs.---"Diet sounds like this wholesome way to treat seizures, but it's very hard. I mean, diets in general are hard, and this diet is really hard," said Yellen, whose wife's Center for Dietary Therapy in Epilepsy hosts a candy-free Halloween party for its many patients on the ketogenic diet. "So finding a pharmacological substitute for this would make lots of people really happy."---Story Source-The above story is reprinted from materials provided by Harvard Medical School. The original article was written by R. Alan Leo. --Journal Reference--Alfredo Giménez-Cassina, Juan Ramón Martínez-François, Jill K. Fisher, Benjamin Szlyk, Klaudia Polak, Jessica Wiwczar, Geoffrey R. Tanner, Andrew Lutas, Gary Yellen, Nika N. Danial. BAD-Dependent Regulation of Fuel Metabolism and KATP Channel Activity Confers Resistance to Epileptic Seizures. Neuron, 2012; 74 (4): 719 DOI: 10.1016/j.neuron.2012.03.032
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Glucose Deprivation Activates Feedback Loop That Kills Cancer Cells
In cancer cells, glucose starvation activates a metabolic and signaling feedback loop leading to cell death. Glucose starvation induces generation of reactive oxygen species generation (ROS), thereby inhibiting phosphatases and activating tyrosine kinases, which in turn generate additional ROS. This glucose starvation-induced positive feedback loop amplifies ROS levels until cells undergo ROS-mediated cell death. ---ScienceDaily (June 26, 2012) — Compared to normal cells, cancer cells have a prodigious appetite for glucose, the result of a shift in cell metabolism known as aerobic glycolysis or the "Warburg effect." Researchers focusing on this effect as a possible target for cancer therapies have examined how biochemical signals present in cancer cells regulate the altered metabolic state.---Now, in a unique study, a UCLA research team led by Thomas Graeber, a professor of molecular and medical pharmacology, has investigated the reverse aspect: how the metabolism of glucose affects the biochemical signals present in cancer cells.---In research published June 26 in the journal Molecular Systems Biology, Graeber and his colleagues demonstrate that glucose starvation -- that is, depriving cancer cells of glucose -- activates a metabolic and signaling amplification loop that leads to cancer cell death as a result of the toxic accumulation of reactive oxygen species, the cell-damaging molecules and ions targeted by antioxidants like vitamin C.---The research, which involved UCLA scientists from the Crump Institute for Molecular Imaging, the Institute for Molecular Medicine, the California NanoSystems Institute, the Jonsson Comprehensive Cancer Center, the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, and the Department of Pathology and Laboratory Medicine, demonstrates the power of systems biology in uncovering relationships between metabolism and signaling at the network level.---"Most strikingly, our discovery that glucose withdrawal causes both cell death and increased tyrosine phosphorylation is intriguing because increased tyrosine kinase signaling is normally associated with cell growth," said Nicholas A. Graham, a senior postdoctoral scholar in Graeber's lab who helped design the project.---To explain the seemingly contradictory result that glucose deprivation reduced viability and at the same time increased signaling, the authors used an unbiased systems-biology approach that included phospho-tyrosine mass spectrometry and other biochemical profiling techniques.---Assessing the "crosstalk" between metabolism and signaling, they discovered that the glucose deprivation activates a positive feedback loop whereby the withdrawal of glucose induces increased levels of reactive oxygen species, which in turn inhibit negative regulators of tyrosine signaling. The resulting supra-physiological levels of tyrosine phosphorylation then generate additional reactive oxygen species.---"Because cancer cells live on the edge of what is metabolically feasible, this amplifying cycle of oxidative stress ultimately overwhelms and kills the cancer cell," Graeber explained. "These findings illustrate the delicate balance that exists between metabolism and signaling in the maintenance of cancer cell homeostasis."---In addition, the authors showed the possibility of exploiting this positive feedback loop for therapeutic intervention. Combining short-term glucose deprivation with an inhibitor of tyrosine phosphatases, they demonstrated synergistic cell death in a cancer cell line.---"Understanding the links between metabolism and signaling will empower new therapeutic approaches toward inducing this metabolic catastrophe," Graham said. "This study provides a framework for rational design of combinatorial therapeutics targeting both metabolism and signaling in cancer."---The findings by Graeber and his colleagues add to the emerging concept of systems integration between oncogenic signaling networks and the metabolism of malignant tumors. The work lays a foundation for future studies delineating how signaling and metabolism are linked, with the ultimate goal of refining therapeutic strategies targeting cancer metabolism.---The research team also included collaborators from the department of neurology and the human oncology and pathogenesis program at Memorial Sloan-Kettering Cancer Center and the department of pharmacology at Weill-Cornell Medical College.---The research was funded by the National Institutes of Health, UCLA's Jonsson Comprehensive Cancer Center, and the California Institute of Technology-University of California, Los Angeles, Joint Center for Translational Medicine.---Story Source-The above story is reprinted from materials provided by University of California - Los Angeles. The original article was written by Jennifer Marcus. --Journal Reference-Nicholas A Graham, Martik Tahmasian, Bitika Kohli, Evangelia Komisopoulou, Maggie Zhu, Igor Vivanco, Michael A Teitell, Hong Wu, Antoni Ribas, Roger S Lo, Ingo K Mellinghoff, Paul S Mischel, Thomas G Graeber. Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. Molecular Systems Biology, 2012; 8 DOI: 10.1038/msb.2012.20
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Drinking Coffee with Caffeine may Reduce the risk of Basal Cell Carcinoma
Drinking coffee with caffeine may reduce the risk of basal cell carcinoma, the most common form of skin cancer, a new study suggests. ---"Our data indicate that the more caffeinated coffee you consume, the lower your risk of developing basal cell carcinoma," said Jiali Han, associate professor at Brigham and Women's Hospital, Harvard Medical School in Boston and Harvard School of Public Health. The findings add to other apparent benefits of coffee, which has been at least suggestively linked to lower risk of depression in women and may counteract cognitive decline. Coffee may even help prevent Alzheimer’s, Parkinson’s disease and type 2 diabetes. [Coffee Habits: Infographic] ---
“Our results add basal cell carcinoma to a list of conditions for which risk is decreased with increasing coffee consumption,” Han in a statement. “This list includes conditions with serious negative health consequences such as type 2 diabetes and Parkinson's disease."--- Han and his colleagues studied data from the Nurses' Health Study, a large and long-running study to aid in the investigation of factors influencing women's health, and the Health Professionals Follow-up Study, a similar study for men.---Of the 112,897 participants included in the analyses, 22,786 developed basal cell carcinoma during the more than 20 years of follow-up in the two studies, the researchers explained in a statement. Lower risk of developing basal cell carcinoma was linked to consumption of caffeinated coffee as well as caffeine from other sources: tea, cola and chocolate. Decaffeinated coffee did not have the same effect.---"These results really suggest that it is the caffeine in coffee that is responsible for the decreased risk of basal cell carcinoma associated with increasing coffee consumption," Han said. "This would be consistent with published mouse data, which indicate caffeine can block skin tumor formation. However, more studies in different population cohorts and additional mechanistic studies will be needed before we can say this definitively."---No link was established between caffeine consumption and risk for two other forms of skin cancer, squamous cell carcinoma and melanoma, the most deadly form of the disease.---The findings are detailed in Cancer Research, a journal of the American Association for Cancer Research.
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Moderate Coffee Consumption Offers Protection Against Heart Failure
New research shows a possible benefit from coffee consumption, but like with so many other things we consume, it really depends on how much coffee you drink, the researchers say. ---ScienceDaily (June 26, 2012) — While current American Heart Association heart failure prevention guidelines warn against habitual coffee consumption, some studies propose a protective benefit, and still others find no association at all. Amidst this conflicting information, research from Beth Israel Deaconess Medical Center attempts to shift the conversation from a definitive yes or no, to a question of how much.---"Our results did show a possible benefit, but like with so many other things we consume, it really depends on how much coffee you drink," says lead author Elizabeth Mostofsky, MPH, ScD, a post-doctoral fellow in the cardiovascular epidemiological unit at BIDMC. "And compared with no consumption, the strongest protection we observed was at about four European, or two eight-ounce American, servings of coffee per day."---The study published June 26 online in the journal Circulation: Heart Failure, found that these moderate coffee drinkers were at 11 percent lower risk of heart failure.---Data was analyzed from five previous studies -- four conducted in Sweden, one in Finland -- that examined the association between coffee consumption and heart failure. The self-reported data came from 140,220 participants and involved 6,522 heart failure events.---In a summary of the published literature, the authors found a "statistically significant J-shaped relationship" between habitual coffee consumption and heart failure, where protective benefits begin to increase with consumption maxing out at two eight-ounce American servings a day. Protection slowly decreases the more coffee is consumed until at five cups, there is no benefit and at more than five cups a day, there may be potential for harm.---It's unclear why moderate coffee consumption provides protection from heart failure, but the researchers say part of the answer may lie in the intersection between regular coffee drinking and two of the strongest risk factors for heart failure -- diabetes and elevated blood pressure.--"There is a good deal of research showing that drinking coffee lowers the risk for type 2 diabetes, says senior author Murray Mittleman, MD, DrPH, a physician in the Cardiovascular Institute at Beth Israel Deaconess Medical Center, an Associate Professor of Medicine at Harvard Medical School and director of BIDMC's cardiovascular epidemiological research program. "It stands to reason that if you lower the risk of diabetes, you also lower the risk of heart failure."---There may also be a blood pressure benefit. Studies have consistently shown that light coffee and caffeine consumption are known to raise blood pressure. "But at that moderate range of consumption, people tend to develop a tolerance where drinking coffee does not pose a risk and may even be protective against elevated blood pressure," says Mittleman.--This study was not able to assess the strength of the coffee, nor did it look at caffeinated versus non-caffeinated coffee.---"There is clearly more research to be done," says Mostofsky. "But in the short run, this data may warrant a change to the guidelines to reflect that coffee consumption, in moderation, may provide some protection from heart failure."--Other study authors are Megan Rice, Sc.D., and Emily Levitan, Sc.D.-The research was supported by grants from the National Institutes of Health.--Story Source-The above story is reprinted from materials provided by Beth Israel Deaconess Medical Center, via Newswise.
[U1]GMO Babies are being made these are the prototypes of the futuristic slaves to come---will be made in a lab---and for the rest of us---GMO foods for GMO babies---and GMO foods do not work with Created beings made by God through Conception--HUMAN
[U2]UN-*&^^%$ believable---they are going to dictate what you can eat –how you are supposed to live and conduct yourselves---and what to believe and think!!?
[U3]Isn’t this interesting –this is already going on with the lunacy of ---the GREEN ---all HS but again this is where everyone s being led to a state of sterility---a sterile culture –controlled by AI thinking—linked to a central intelligence that would run us like programmed drones---we do not feel anything for another human being just being and serving---robots or humanoids with no creativity no brain just do
[U4]And who decides who has what and who does what and where is your rank in this---they would set this up like a hierarchal pyramid and everyone would kiss butt to get at a top rank which really mean you are more inducted to become more connected to an AI which would be run by an alien presence-----Does this not sound like outside intervention by a dark force?? Where is freedom of choice here?!
[U5]This is where we get double speak –an orwellan term—say one thing mean the opposite---with the INCENTIVESS---people who have no morals and are reptilian in nature will grasp this –reptillians have no long term association or love of family ---they drop them and dump them or even turn on there own kind
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Show of the Month July 13 2012
Unprecedented--Class Action Lawsuit against Church, State and Big Pharma given Green Light
The Key (Proteins) to Self-Renewing Skin
How to make Serum Vitamin C for internal and External Use
Simple Exercises Are an Easy and Cost-Effective Treatment for Persistent Dizziness
Vertigo Can Be Treated Easily And Quickly
Canalith repositioning procedure for right-sided benign paroxysmal positional vertigo
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Unprecedented--Class Action Lawsuit against Church, State and Big Pharma given Green Light
Activist Post---Toronto, Canada – History was made yesterday when a legal team headed by Jason Bowman of the ACP was granted the right to proceed with its filing of a criminal conspiracy lawsuit against the Vatican, Crown of England and other parties.--A Federal Court judge in Toronto examined the material and granted leave for the full application to be filed and presented in court next Monday, July 9.----According to Bowman, who acted on behalf of both the ACP and ITCCS,-We expected to simply file a motion … Instead, the Court directed that we file not only the ex-parte motion materials, but also our entire Application a full week earlier than we were expecting. Naturally, I was elated.
A crowd of supporters accompanied Bowman to the Federal Court where he secured a preliminary hearing and approval to proceed from the on duty judge.----Afterwards, the group held a press conference nearby and was harassed by security guards and at least one agent provocateur named Greg Renouf who tried to incite violence and discredit both Bowman and ITCCS founder and co-applicant Kevin Annett. Renouf has since then posted a derogatory and untruthful YouTube posting about the event.[U1]---An attempted livestream broadcast of the event was inexplicably disrupted, although blog media activists who were present reported the news extensively on the Internet.---None of the “mainstream” media in Toronto attended the press conference.[U2]---The ACP-ITCCS lawsuit is the first of its kind: a class action aimed at so-called heads of state, including the Pope and the Queen of England, on behalf of victims of alleged crimes against humanity committed by churches, governments and corporations.----
Also named in this suit as defendants are the government of Canada, the United Church of Canada, the Church of England, and pharmaceutical companies, all of which are charged with crimes against humanity and criminally conspiring to obstruct justice.----Kevin Annett, who is named in the court application as a plaintiff against the Crown, Pope and other defendants, commented, As usual, the corporate media ignored us and paid operatives tried to discredit and stop us, but this time, we got our foot in the door of the court system. Wherever that leads us, we’ve taken another step towards forcing criminals in power to do time for their crimes. Whether it’s in this court or in a common law de jure one, the tables will be turned.---Stay tuned for you tube postings, and more updates after the July 9 court appearance, at www.itccs.org and http://federalclassactions.wordpress.com
For videos and other footage see:
http://federalclassactions.wordpress.com/2012/07/04/update-historical-application-to-be-filed-and-served-upon-the-vatican-the-queen-others-court-directs-applicants-in-chambers-today-re-mondays-ex-parte-motion/
See the evidence of Genocide in Canada and other crimes against the innocent at www.hiddennolonger.com and at the website of The International Tribunal into Crimes of Church and State at www.itccs.org.
Messages for Kevin Annett can be left at 250-591-4573 (Canada).
Watch Kevin's award-winning documentary film Unrepentant on his website www.hiddenfromhistory.org**************************************************************************
The Key (Proteins) to Self-Renewing Skin
ScienceDaily (July 5, 2012) — In the July 6 issue of Cell Stem Cell, researchers at the University of California, San Diego School of Medicine describe how human epidermal progenitor cells and stem cells control transcription factors to avoid premature differentiation, preserving their ability to produce new skin cells throughout life.--The findings provide new insights into the role and importance of exosomes and their targeted gene transcripts, and may help point the way to new drugs or therapies for not just skin diseases, but other disorders in which stem and progenitor cell populations are affected.---Stem cells, of course, are specialized cells capable of endlessly replicating to become any type of cell needed, a process known as differentiation. Progenitor cells are more limited, typically differentiating into a specific type of cell and able to divide only a fixed number of times.----Throughout life, human skin self-renews. Progenitor and stem cells deep in the epidermis constantly produce new skin cells called keratinocytes that gradually rise to the surface where they will be sloughed off. One of the ways that stem and progenitor cells maintain internal health during their lives is through the exosome -- a collection of approximately 11 proteins responsible for degrading and recycling different RNA elements, such as messenger RNA that wear out or that contain errors resulting in the translation of dysfunctional proteins which could potentially be deleterious to the cell.---"In short," said George L. Sen, PhD, assistant professor of medicine and cellular and molecular medicine, "the exosome functions as a surveillance system in cells to regulate the normal turnover of RNAs as well as to destroy RNAs with errors in them."-----Sen and colleagues Devendra S. Mistry, PhD, a postdoctoral research fellow, and staff scientist Yifang Chen, MD, PhD, discovered that in the epidermis the exosome functions to target and destroy mRNAs that encode for transcription factors that induce differentiation. Specifically, they found that the exosome degrades a transcription factor called GRHL3 in epidermal progenitor cells, keeping the latter undifferentiated. Upon receiving differentiation inducing signals, the progenitor cells lose expression of certain subunits of the exosome which leads to higher levels of GRHL3 protein. This increase in GRHL3 levels promotes the differentiation of the progenitor cells.----"Without a functioning exosome in progenitor cells," said Sen, "the progenitor cells prematurely differentiate due to increased levels of GRHL3 resulting in loss of epidermal tissue over time."-----Sen said the findings could have particular relevance if future research determines that mutations in exosome genes are linked to skin disorders or other diseases. "Recently there was a study showing that recessive mutations in a subunit of the exosome complex can lead to pontocerebellar hypoplasia, a rare neurological disorder characterized by impaired development or atrophy of parts of the brain," said Sen. "This may potentially be due to loss of progenitor cells. Once mutations in exosome complex genes are identified in either skin diseases or other diseases like pontocerebellar hypoplasia, it may be possible to design drugs targeting these defects."
Funding for this research came, in part, from the National Institutes of Health grant K01AR057828-04 and a Ray Thomas Edwards Award.---Story Source-The above story is reprinted from materials provided by University of California, San Diego Health Sciences. --Journal Reference-Devendra S. Mistry, Yifang Chen, George L. Sen. Progenitor Function in Self-Renewing Human Epidermis is Maintained by the Exosome. Cell Stem Cell, 6 July 2012; 11(1) pp. 127 - 135 DOI: 10.1016/j.stem.2012.04.022
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How to make Serum Vitamin C for internal and External Use
Vitamin C serum Active Ingredient : 1-1.2 grams Vitamin C (L-ascorbic acid) (approximately 1/4 teaspoon) (The active ingredient must be L-ascorbic acid, not vitamin C tablets, or calcium Ascorbate) This can also be purchased from Skin Actives.
Base Ingredients. 5 ml glycerine (1 teaspoon) 5ml water (1 teaspoon) You should be able to buy both the L-ascorbic acid and glycerine from your chemist store.
Process. 1. Dissolve 1gram of L-ascorbic acid in 5 ml of water (preferably distilled), in small glass container using a stirrer. Make sure it is fully dissolved before proceeding to next step.
2. Add 5 ml of glycerine and mix.
3. Put in a sealable jar, (not clear glass as this allows light in, and light degrades vitamin C.) Store in cool dry place.
Voila – your own fresh vitamin C serum. Apply to skin once per day to start with (preferably at night), and increase to twice daily if tolerated.
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Simple Exercises Are an Easy and Cost-Effective Treatment for Persistent Dizziness
ScienceDaily (July 5, 2012) — A professor from the University of Southampton has called on doctors around the world to give patients with persistent dizziness a booklet of simple exercises, after new research has shown that it is a very cost effective treatment for common causes of the condition.----Lucy Yardley, who has been researching dizziness for many years, will urge GPs at the international WONCA conference July 5 to ensure that the booklet is translated so that patients of all nationalities can benefit.---Professor Yardley's urgent appeal comes after her study, funded by the National Institute for Health Research (NIHR) and published in the British Medical Journal, revealed that the exercises, such as turning your head right to left and back again or nodding your head up and down, led to reduced dizziness within a matter of weeks of starting, and the benefits lasted for at least a year.---Dizziness is a common condition, especially among older people, but it can affect any age. It can interfere with people's daily activities and cause stress. It also increases the risk of falling and fear of falling, which in turn, can result in substantial further limitation of activity, injury, and healthcare costs.---Research has shown that an exercise-based treatment known as "vestibular rehabilitation" or "balance retraining" is the most effective means of treating dizziness related to inner ear problems (a very common cause of dizziness), however currently only about one in ten suitable patients are referred for this treatment.---During the study, which Professor Yardley is presenting at the WONCA conference, more than 300 participants were randomly allocated to receive either routine medical care (commonly just reassurance and medication to suppress dizziness symptoms), booklet based vestibular rehabilitation only, or booklet based vestibular rehabilitation with telephone support from a healthcare professional.----The majority of patients within the study, an NIHR Research for Patient Benefit project, suffered from dizziness due to an inner ear problem, however there were many patients who had undiagnosed dizziness.---Nearly twice as many patients who had the booklet and telephone support said they felt much better or totally well at the end of the study, compared with those who had routine care. Even without any support, getting the booklet led to better recovery than routine care. Only 5 per cent of patients receiving the booklet with support reported worse symptoms at the end of the study, compared with 15 per cent of those receiving usual care.----Professor Yardley says: "Dizziness can be a frustrating and sometimes frightening condition. Many people are undiagnosed, have no treatment for it and just learn to live with it. This leads to a low quality of life and can have high healthcare costs. By being given something as a simple as a booklet by their GP, that contains these simple head, neck and eye exercises, many patients will see real benefits in just a few weeks. These easy to understand exercises, which can be carried out at home, have the potential to improve the quality of life for thousands of people."---The University of Southampton worked with the Ménière's Society UK during the study. The Society supplied the exercise booklets used in the study and has been giving them to health professionals and members of the public for seven years.----Natasha Harrington-Benton, UK Director of the Society, comments: "Dizziness and balance disorders can be extremely debilitating and affect a person's quality of life. This study demonstrates the benefits of vestibular rehabilitation in helping people to manage the symptoms of their condition. We are pleased to be able to provide access to the exercise booklets for both patients and health professionals and, to-date, we have distributed over 8,000 copies."---Story Source---The above story is reprinted from materials provided by University of Southampton. ----Journal Reference-L. Yardley, F. Barker, I. Muller, D. Turner, S. Kirby, M. Mullee, A. Morris, P. Little. Clinical and cost effectiveness of booklet based vestibular rehabilitation for chronic dizziness in primary care: single blind, parallel group, pragmatic, randomised controlled trial. BMJ, 2012; 344 (jun06 1): e2237 DOI: 10.1136/bmj.e2237
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Vertigo Can Be Treated Easily And Quickly
ScienceDaily (May 26, 2008) — A new guideline developed by the American Academy of Neurology found that the best treatment for vertigo is the easiest and quickest one. The guideline on benign paroxysmal positional vertigo (BPPV), an inner ear disorder that is a common cause of dizziness, is published in the May 27, 2008, issue of Neurology.---The disorder causes a feeling of spinning or whirling when the head is moved in certain ways, such as looking up or bending. The feeling lasts a short time but can be severe.--The guideline determined that in many cases the vertigo can be treated with simple maneuvers--a series of head and body movements performed by a doctor or therapist while the patient sits on a bed or table.---"The good news is that this type of vertigo is easily treated," said guideline author Terry D. Fife, MD, of the University of Arizona College of Medicine and Barrow Neurological Institute. Fife is also a Fellow of the American Academy of Neurology. "Instead of telling patients to 'wait it out' or having them take drugs, we can perform a safe and quick treatment that is immediate and effective."
Several maneuvers are in use for vertigo. The guideline found that canalith repositioning procedure, also called the Epley maneuver, is safe and effective for people of all ages. The Semont maneuver is possibly an effective treatment. To develop the guideline, the authors analyzed all available scientific studies on the topic.----The disorder is believed to be caused by loose calcium carbonate crystals that move in the sensing tubes of the inner ear. The maneuvers move the calcium crystals out of the sensing tube and into another inner chamber of the ear, from which they can be absorbed.---The guideline also evaluated whether restrictions on activity are needed after the maneuvers are performed. "There is no clear evidence to support these restrictions, which include sleeping upright and wearing a cervical collar," Fife said.---The guideline also reviewed whether patients can perform the maneuvers safely and effectively at home. "Having patients treat themselves using home exercises seems to pose little risk, but there is not sufficient evidence that this is as effective as maneuvers done by a doctor or therapist," Fife said.---Story Source--The above story is reprinted from materials provided by American Academy of Neurology.
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Canalith repositioning procedure for right-sided benign paroxysmal positional vertigo.
Or
Steps 1 and 2 are identical to the Dix–Hallpike maneuver. The patient is held in the right head hanging position (Step 2) for 20 to 30 seconds, and then in Step 3 the head is turned 90 degrees toward the unaffected side. Step 3 is held for 20 to 30 seconds before turning the head another 90 degrees (Step 4) so the head is nearly in the face-down position. Step 4 is held for 20 to 30 seconds, and then the patient is brought to the sitting up position. The movement of the canalith material within the labyrinth is depicted with each step, showing how canaliths are moved from the semicircular canal to the vestibule. Although it is advisable for the examiner to guide the patient through these steps, it is the patient’s head position that is the key to a successful treatment. (Figure from Fife, et al. Neurology 2008;70:2067-74)
To view a video demonstration link to
http://www.neurology.org/cgi/content/full/70/22/2067/DC2
[U1]Seems like someone pissed in someone’s cornflakes---and were not to happy!!
[U2]What a Surprise eh!!! Mainstream did Not show up----now I would have been surprised if they actually did!!!
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Three coffees a day keeps dementia away
Drinking three cups of coffee a day could reduce the risk of Alzheimer’s disease, according to a study by Florida-based researchers.
Keeping high blood caffeine levels by drinking coffee was found to help at-risk adults over 65 to avoid the onset Alzheimer’s disease.--The study by Chuanhai Cao et al. was published online today ahead of publication in the Journal of Alzheimer’s disease.
Coffee: main caffeine source for study participants
The researchers monitored the cognitive status of 124 people aged between 65 and 88 displaying mild cognitive impairment (MCI), an early sign of the disease. Many participants were expected to develop Alzheimer’s within a few years.---No MCI patients with a blood caffeine level above 1,200 ng/ml developed the disease over a 2-4 year period. The main or only caffeine source for these individuals was coffee.---Study lead author and neuroscientist Chuanhai Cao, said: “These intriguing results suggest that older adults with mild memory impairment who drink moderate levels of coffee -- about 3 cups a day -- will not convert to Alzheimer's disease -- or at least will experience a substantial delay before converting to Alzheimer's,"--"The results from this study, along with our earlier studies in Alzheimer's mice, are very consistent in indicating that moderate daily caffeine/coffee intake throughout adulthood should appreciably protect against Alzheimer's disease later in life," he continued.--Reduced risk, but no complete protection---The researchers claim the study is the first to provide a direct link between caffeine/coffee intake and reduced Alzheimer’s risk or delayed onset.--“We are not saying that moderate coffee consumption will completely protect people from Alzheimer's disease," Cao continued.---"However, we firmly believe that moderate coffee consumption can appreciably reduce your risk of Alzheimer's or delay its onset."---Other coffee perks--In the past year alone, coffee has been linked to a series of health benefits.---In Feburary, NutraIngredients.com reported on a study that found high consumption of coffee could reduce the risk of advanced fibrosis in those with fatty liver disease.---Another recent study found that the caffeine laden drink could reduce the risk of womb (endometrial) cancer, while other research has linked coffee to reduced diabetes risk.----Citation--Study: ‘High Blood Caffeine Levels in MCI Linked to Lack of Progression to Dementia ,’ Journal of Alzheimer’s Disease 30 (2012) 559–572 DOI 10.3233/JAD-2012-111781-By Chuanhai Caoa, David A. Loewensteine, Xiaoyang Linc, Chi Zhangc, Li Wangc, Ranjan Duarae, Yougui Wuh, Alessandra Gianninid, Ge Baii, Jianfeng Caii, Maria Greige,, Elizabeth Schofielde, Raj Ashokc, Brent Smallj, Huntington Potterc,k and Gary W. Arendashd,
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Prebiotics may enhance magnesium uptake from diet
Prebiotic fibers may enhance the absorption and retention in rats, suggests new data from Purdue University with implications for bone health in postmenopausal women.---Supplementation of the diet with commercial ingredients Synergy1 (Beneo), Fruitafit HD (Sensus) or polydextrose (Tate & Lyle) was associated with an increase in magnesium absorption and retention of about 20% and 23%, respectively, according to findings published in the Journal of Food Science.---Explaining the practical implications of their findings, the researchers note: “Steady growth in US middle-aged and elderly populations has led to higher incidences of several chronic diseases including osteoporosis, a bone disease that primarily affects postmenopausal women. Recent research suggests that certain dietary fibers (prebiotics) enhance mineral absorption and may impart bone health benefits. ----“Study findings will aid future investigations in ascertaining the factors related to potential bone health benefits of prebiotic which will aid in developing an effective prebiotics food product/supplement that will address the bone health needs of consumers.”-Prebiotics---This is not the first time that prebiotics have been reported to beneficially influence magnesium uptake. A study by Cargill and TNO Quality of Life from 2009 (Nutrition Research, Vol. 29, pp. 229-237) indicated that fructo-oligosaccharide consumption increased magnesium absorption in 12- to 15-year-old girls by 18% after 36 days.---The potential benefits of prebiotics include improved bone health, colon health, immunity, satiety, and weight management.--The chicory root is the major source of prebiotic ingredients. Inulin and oligofructose are the two major ingredients sourced from the root that is mainly grown in Belgium and Northern France where the world’s ‘big three’ suppliers (Beneo-Orafti, Sensus, Cosucra) are based.---Study details---The Purdue scientists divided female lab rats into six groups. The first group acted as the controls, while the other five groups had their ovaries removed to act as a model of post-menopausal conditions. One of the ovariectomized rat groups was fed the control diet only, one group received daily estradiol (E2) injections, and the other three groups had their daily diet supplemented with Synergy1, Fruitafit HD, or polydextrose at a level of 5%.-The researchers found that the polydextrose-fed rats had higher calcium absorption efficiency and retention than the other groups after a few days, but this difference was no longer observed after four weeks of feeding.--Both inulin-based fibers (Synergy1 and Fruitafit HD) produced positive effects on calcium metabolism related to changes in the gut, they said.--“Although prebiotics increased mineral absorption and utilization, the increase did not translate to improved indicators of bone strength suggesting that a four week dietary prebiotics treatment may not be sufficient to have a substantial impact on bone after stabilization following menopause,” they noted. “Longer treatment duration as well as administration of treatment during growth or early or perimenopausal phase may produce larger benefits.”----Source: Journal of Food Science --Volume 77, Issue 4, Pages H88-94, doi: 10.1111/j.1750-3841.2011.02612.x “Prebiotics enhance magnesium absorption and inulin-based fibers exert chronic effects on calcium utilization in a postmenopausal rodent model” Authors: L.L. Legette, W. Lee, B.R. Martin, J.A. Story, J.K. Campbell, C.M. Weaver
Recipe---take the yogurt of choice( plain and with fat) and add a magnesium capsule ( whatever you are using) or a liquid form of magnesium( 1 tsp of a liquid) mix it well in the yogurt container or bowl---then allow it to sit out over night allowing the fermentation to take place---next day consume the allotted container—this will increase the uptake---to see the results this may have to be utilized for an extended period of time
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Homemade Citrus Pectin
The white parts of citrus peels are naturally high in pectin
Pectin is a naturally occurring substance in fruit that makes sweet preserves gel. However, some fruits are low in pectin and need added pectin in order to gel. You can buy commercial pectin, or you can make your own from citrus peels. You can also make pectin from apples.
High-pectin citrus peel is what makes marmalade gel without added pectin. Keep in mind that it is the white pith, or inner part of the citrus peel that is rich in pectin. Under-ripe fruits have more of this pith than fully ripe fruits. You can use any citrus for this recipe, but grapefruit works especially well because of its larger pith.
Prep Time: 5 minutes
Cook Time: 15 minutes
Maceration time: 3 hours
Total Time: 3 hours, 20 minutes
Yield: 1 pint
Ingredients:
- ½ lb white parts of citrus peels
- 2 cups water
- ¼ cup lemon juice
Preparation:
Remove the colorful zest of the peels with a zester or vegetable peel. Set aside for another use (wonderfully aromatic and flavorful, this zest could overwhelm the flavors of other fruits in your jams and jellies). Cut off white parts, finely chop and weigh.
Combine the chopped citrus peel pith with the lemon juice in a medium sized pot. Let stand for 2 hours. Add the water and let stand for another hour.
Bring the mixture to a boil over high heat. Reduce heat and simmer for 15 minutes. Remove from heat and let cool.
Strain through a jelly bag or several layers of cheesecloth. The liquid pectin will keep in the refrigerator for a week, or in the freezer for 6 months.
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Pectin made from citrus fruit
Pectin is concentrated mainly in the peel - in the white, inner part of the skin (pith), in the membranes between the sections and in the seeds. Citrus fruit produces a lot of super jelling pectin, but it has a pronounced flavor which comes from the slightly bitter pith. The membranes and seeds have a neutral flavor. Underripe fruit posseses thick skins and will produce more pectin than a fully matured fruit. The fully ripe fruit left on the tree will have even thinner skin and only a little pectin.---What follows below is the excellent formula for citrus pectin from an old document: Stennis, M.A., “Citrus Conservation” Florida Fruits and Vegetables in the Commercial Menu, State of Florida Department of Agriculture, Tallahassee, 1931.
½ lb white part (pith) of orange peel, about 8 oranges may be needed.
1 pint (2 cups) of water
4 Tbsp. lemon juiceThe more pronounced flavor of a lemon pectin base means it's most suited for a jam or jelly where you want the lemon flavor.
Instructions
Peel the oranges, you should have 4 skin quarters. Cut those quarters into narrower strips and remove the white peel with a knife. Chop the white peel through a food processor or cut with a knife.
Mix grated white peel with lemon juice and allow to stand for 1 hour. Add 1 pint of water and set it aside for another hour.
Boil gently 10 minutes. Switch off the heat, cover and let the pot cool. Perform the pectin alcohol test.
Drain and filter.
Store in refrigerator.
Second extraction
After the pectin stock was drained away, the pulp can be mixed with 3/4 pint of water again and reboiled gently for 10 minutes. Then it should be cooled and drained. If the alcohol test shows that the pectin stock is too thin, it can be simmered for 10 minutes to evaporate some water. Both extractions may be mixed together.
If a pectin stock satisfies the alcohol test, it will gel and the jelly will set. Apple or orange pectin stock can be used for making apple or orange jelly, or it may be added to other fruits and juices that are pectin poor. For example, strawberries, pears, blueberries, and apricots are pectin poor and will benefit if a solid pectin stock is added. People knew nothing about pectin but it was a well known fact that it was easier to make strawberry pectin if some apples were added.
Left glass - apple pectin, Right glass - orange pectin
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Unfounded claims against apple pectin
Lengfelder, Frenzel and Kenigsberg claimed that pectin had no useful properties. According to them, a study had been conducted by Herbstreith and Fox in Germany had proved that pectin was ineffective in decorporation (removing from body) of radionuclides. When a representative from Herbstreith and Fox was later interviewed, he said that only the effect of apple pectin on heavy metals had been studied, not the effect on radionuclide (p.137 of [1]). ---But in a letter sent from the Ministry of Health of the Russian Federation in 2003 to local health authority directors, the pectin product Zosterine-Ultra was recommended as a “mass prophylactic in the atomic industry [with] the capacity to eliminate from the body the toxic components of lead, mercury, cadmium, zinc, manganese and other heavy metals as well as radionuclides including plutonium.” It was “perfectly tolerated by patients and has no contra indications.” The letter went on to say how important this product has been in the Chernobyl area in “lowering the levels of accumulation and concentration of toxic substances in the body, and reinforcing the body’s own defence mechanisms.” And the product has been “approved as a therapeutic and prophylactic food additive by various medical research institutes, hospitals and clinics, including the State Scientific Centre, Institute of Biophysics, the Institute of Research of the Academy of Medical Science of Russia, the Kirov Academy of Military Medicine, the Institute of Toxicology at the Ministry for Public Health in Russia, the Academy of Ongoing Medical Training (Saint Petersberg).” In short, it was a ringing endorsement from the Russian Ministry of Health.
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Air in Expectant Moms' Homes Contains Pesticides, Texas-Mexico Border
Astragaloside IV and cycloastragenol stimulate
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Air in Expectant Moms' Homes Contains Pesticides, Texas-Mexico Border Study Finds
ScienceDaily (July 11, 2012) — Air samples from homes of Hispanic mothers-to-be along the Texas-Mexico border contained multiple pesticides in a majority of the houses, according to a study conducted by the School of Medicine at The University of Texas Health Science Center San Antonio.---All the women were in the third trimester of pregnancy, when the fetal brain undergoes a growth spurt. Several studies have reported that pesticide exposure may adversely affect mental and motor development during infancy and childhood. The new report is in the summer issue of the Texas Public Health Journal sent to members this week.---Two-thirds of the families surveyed said they used pest control methods to kill cockroaches, rodents and other pests. Pregnant women and infants often spend 90 percent of their day indoors.----"There is a lack of education in our communities regarding the health hazards of these toxic pest control methods," said lead author Beatriz Tapia, M.D., M.P.H., lecturer at the UT Health Science Center -- Regional Academic Health Center campus in Harlingen, located 10 miles from the border. "We should concentrate on trying to educate families about low-cost methods that prevent infestations and use the least toxic pest control methods first."-----A wise alternative---Integrated pest management (IPM) is a low-cost strategy to replace the use of residential pesticides, Dr. Tapia said. IPM focuses on installing screens and caulking doors and windows to keep out pests, putting away food and placing boric acid, a low-impact alternative, in walls.---"Once we educate our women of childbearing age about how they can safely and in a healthy manner diminish pests in their homes, they will feel empowered that they can make a difference in their family's life," Dr. Tapia said. She is a faculty associate in the university's Department of Family and Community Medicine and serves as environmental medicine training coordinator for the South Texas Environmental Education and Research Center (STEER). She co-coordinates a 30-day Harlingen student elective in environmental and occupational medicine.
Samples show presence---The team sampled air in 25 households, finding at least five pesticides in 60 percent of the dwellings. Nine other pesticides were identified in less than one-third of the homes.---Ninety-two percent of the air samples contained o-phenylphenol, which is used as a fungicide, germicide and household disinfectant, while 80 percent included chlorpyrifos, employed in agriculture to kill mosquitoes and other pests. Propoxur, present in granular baits, pet collars and other products, showed up in 76 percent of samples, along with the insecticide diazinon in 72 percent. The herbicide trifluralin turned up in 60 percent of samples.---The U.S. Environmental Protection Agency (EPA) in June 2000 entered into an agreement to eliminate virtually all homeowner uses of chlorpyrifos, except ant and roach baits in child-resistant packaging. The EPA banned residential use of diazinon as of Dec. 31, 2004.
Pregnancy and pesticides don't mix-----"Increasingly, pesticide exposures are being linked to neurodevelopmental disorders such as autism and attention deficit hyperactivity disorder (ADHD)," said co-author and STEER Director Claudia S. Miller, M.D., M.S., professor in environmental and occupational medicine with the Department of Family and Community Medicine. "Planning for pregnancy today should include not only prenatal vitamins and a good diet, but also avoiding potentially hazardous pesticides. Instead, use non-toxic approaches for pest control and IPM."---Environmental medicine researchers at the Harlingen campus modeled the pilot project on studies conducted by the Columbia Center for Children's Environmental Health. These studies, which sampled air in homes of mother/newborn pairs in northern Manhattan or South Bronx, showed that fetal and childhood exposure to pesticides can be measured in indoor air and can adversely affect fetal growth in a minority population.[U1]
Young Hispanics recruited----The Harlingen researchers recruited pregnant Hispanic women from two maternity clinics in Hidalgo County. Enrolled women were 18-35 years old, had no serious medical conditions and had reached 30-34 weeks of gestation. The team asked the women questions about pesticide use and exposure, proximity to agricultural fields, and how often they saw spraying operations or detected pesticide or other odors drifting from fields.---Air samples were measured for multiple pesticides used in agriculture, given the close proximity of the fields to participant homes. These pesticides turned up in 12 percent of the homes, not as high a number as expected. "The reality is, when these pesticides are used outdoors, the sun and soil do their part and eliminate them from the environment," Dr. Tapia said. "Indoors you don't have nature helping you."
Outdoor exposures may not be reflected-----Outdoor and indoor exposures are measured differently. "Agricultural spraying tends to result in shorter-term bursts, so-called acute exposures that may not be captured in a study like ours," Dr. Miller said. "This is a limitation of most pesticide exposure studies in agricultural areas."------Story Source-The above story is reprinted from materials provided by University of Texas Health Science Center at San Antonio, via EurekAlert!, a service of AAAS.
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Hormone-mimicking chemicals released into rivers have been found to impact the mating choices of fish, a new study has revealed. The controversial chemical BPA, which emits estrogen-like properties, was found to alter an individual's appearance and behavior, leading to inter-species breeding. ----ScienceDaily (July 11, 2012) — Hormone-mimicking chemicals released into rivers have been found to impact the mating choices of fish, a new study has revealed. The controversial chemical BPA, which emits estrogen-like properties, was found to alter an individual's appearance and behavior, leading to inter-species breeding. The study, published in Evolutionary Applications, reveals the threat to biodiversity when the boundaries between species are blurred.---The research, led by Dr Jessica Ward from the University of Minnesota, focused on the impact of Bisphenol A (BPA) on Blacktail Shiner (Cyprinella venusta) and Red Shiner (Cyprinella lutrensis) fish which are found in rivers across the United States. BPA is an organic compound used in the manufacture of polycarbonate and other plastics. It is currently banned from baby bottles and children's cups in 11 U.S. states.---"Chemicals from household products and pharmaceuticals frequently end up in rivers and BPA is known to be present in aquatic ecosystems across the United States," said Ward. "Until now studies have primarily focused on the impact to individual fish, but our study demonstrates the impact of BPA on a population level."---The team collected individuals of both species from two streams in the state of Georgia. The species were kept separated for 14 days in tanks, some of which contained BPA. On the 15th day behavioral trials were undertaken as individuals from different tanks were introduced to each other.--The scientists monitored any physiological or signalling differences the individuals displayed, such as color, as well as any behavioral differences during courtship, such as mate choice.---BPA disrupts an individual's endocrine system, which controls the release of hormones. This impacts behavior and appearance, which in turn can lead an individual to mistake a newly introduced species as a potential mate.---This process poses long-term ecological consequences, especially in areas threatened by the introduction of invasive species. BPA and other hormone-mimicking chemicals can escalate the loss of native biodiversity by breaking down species barriers and promoting the invader. "Our research shows how the presence of these human made chemicals leads to a greater likelihood of hybridization between species," concluded Ward. "This can have severe ecological and evolutionary consequences, including the potential for the decline of our native species." ---Story Source- The above story is reprinted from materials provided by Wiley, via AlphaGalileo. -Journal Reference-Jessica L. Ward, Michael J. Blum. Exposure to an environmental estrogen breaks down sexual isolation between native and invasive species. Evolutionary Applications, 2012; DOI: 10.1111/j.1752-4571.2012.00283.x
Hormone-mimicking chemicals released into rivers have been found to impact the mating choices of fish, a new study has revealed. The controversial chemical BPA, which emits estrogen-like properties, was found to alter an individual's appearance and behavior, leading to inter-species breeding. ----ScienceDaily (July 11, 2012) — Hormone-mimicking chemicals released into rivers have been found to impact the mating choices of fish, a new study has revealed. The controversial chemical BPA, which emits estrogen-like properties, was found to alter an individual's appearance and behavior, leading to inter-species breeding. The study, published in Evolutionary Applications, reveals the threat to biodiversity when the boundaries between species are blurred.---The research, led by Dr Jessica Ward from the University of Minnesota, focused on the impact of Bisphenol A (BPA) on Blacktail Shiner (Cyprinella venusta) and Red Shiner (Cyprinella lutrensis) fish which are found in rivers across the United States. BPA is an organic compound used in the manufacture of polycarbonate and other plastics. It is currently banned from baby bottles and children's cups in 11 U.S. states.---"Chemicals from household products and pharmaceuticals frequently end up in rivers and BPA is known to be present in aquatic ecosystems across the United States," said Ward. "Until now studies have primarily focused on the impact to individual fish, but our study demonstrates the impact of BPA on a population level."---The team collected individuals of both species from two streams in the state of Georgia. The species were kept separated for 14 days in tanks, some of which contained BPA. On the 15th day behavioral trials were undertaken as individuals from different tanks were introduced to each other.--The scientists monitored any physiological or signalling differences the individuals displayed, such as color, as well as any behavioral differences during courtship, such as mate choice.---BPA disrupts an individual's endocrine system, which controls the release of hormones. This impacts behavior and appearance, which in turn can lead an individual to mistake a newly introduced species as a potential mate.---This process poses long-term ecological consequences, especially in areas threatened by the introduction of invasive species. BPA and other hormone-mimicking chemicals can escalate the loss of native biodiversity by breaking down species barriers and promoting the invader. "Our research shows how the presence of these human made chemicals leads to a greater likelihood of hybridization between species," concluded Ward. "This can have severe ecological and evolutionary consequences, including the potential for the decline of our native species." ---Story Source- The above story is reprinted from materials provided by Wiley, via AlphaGalileo. -Journal Reference-Jessica L. Ward, Michael J. Blum. Exposure to an environmental estrogen breaks down sexual isolation between native and invasive species. Evolutionary Applications, 2012; DOI: 10.1111/j.1752-4571.2012.00283.x
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THE LAW OF HIPPOCRATES
1. Medicine is of all the arts the most noble; but, owing to the ignorance of those who practice it, and of those who, inconsiderately, form a judgment of them, it is at present far behind all the other arts. Their mistake appears to me to arise principally from this, that in the cities there is no punishment connected with the practice of medicine (and with it alone) except disgrace, and that does not hurt those who are familiar with it. Such persons are the figures which are introduced in tragedies, for as they have the shape, and dress, and personal appearance of an actor, but are not actors, so also physicians are many in title but very few in reality.
2. Whoever is to acquire a competent knowledge of medicine, ought to be possessed of the following advantages: a natural disposition; instruction; a favorable position for the study; early tuition; love of labour; leisure. First of all, a natural talent is required; for, when Nature leads the way to what is most excellent, instruction in the art takes place, which the student must try to appropriate to himself by reflection, becoming an early pupil in a place well adapted for instruction. He must also bring to the task a love of labour and perseverance, so that the instruction taking root may bring forth proper and abundant fruits.
3. Instruction in medicine is like the culture of the productions of the earth. For our natural disposition, is, as it were, the soil; the tenets of our teacher are, as it were, the seed; instruction in youth is like the planting of the seed in the ground at the proper season; the place where the instruction is communicated is like the food imparted to vegetables by the atmosphere; diligent study is like the cultivation of the fields; and it is time which imparts strength to all things and brings them to maturity.
4. Having brought all these requisites to the study of medicine, and having acquired a true knowledge of it, we shall thus, in travelling through the cities, be esteemed physicians not only in name but in reality. But inexperience is a bad treasure, and a bad fund to those who possess it, whether in opinion or reality, being devoid of self-reliance and contentedness, and the nurse both of timidity and audacity. For timidity betrays a want of powers, and audacity a lack of skill. They are, indeed, two things, knowledge and opinion, of which the one makes its possessor really to know, the other to be ignorant.
5. Those things which are sacred, are to be imparted only to sacred persons; and it is not lawful to impart them to the profane until they have been initiated into the mysteries of the science.
The Hippocratic Oath
(Original Version)I SWEAR by Apollo the physician, AEsculapius, and Health, and All-heal, and all the gods and goddesses, that, according to my ability and judgement, I will keep this Oath and this stipulation.
TO RECHON him who taught me this Art equally dear to me as my parents, to share my substance with him, and relieve his necessities if required; to look up his offspring in the same footing as my own brothers, and to teach them this art, if they shall wish to learn it, without fee or stipulation; and that by precept, lecture, and every other mode of instruction, I will impart a knowledge of the Art to my own sons, and those of my teachers, and to disciples bound by a stipulation and oath according the law of medicine, but to none others.
I WILL FOLLOW that system of regimen which, according to my ability and judgment, I consider for the benefit of my patients, and abstain from whatever is deleterious and mischievous. I will give no deadly medicine to any one if asked, nor suggest any such counsel; and in like manner I will not give a woman a pessary to produce abortion.
WITH PURITY AND WITH HOLINESS I will pass my life and practice my Art. I will not cut persons laboring under the stone, but will leave this to be done by men who are practitioners of this work. Into whatever houses I enter, I will go into them for the benefit of the sick, and will abstain from every voluntary act of mischief and corruption; and, further from the seduction of females or males, of freemen and slaves.
WHATEVER, IN CONNECTION with my professional practice or not, in connection with it, I see or hear, in the life of men, which ought not to be spoken of abroad, I will not divulge, as reckoning that all such should be kept secret.
WHILE I CONTINUE to keep this Oath unviolated, may it be granted to me to enjoy life and the practice of the art, respected by all men, in all times! But should I trespass and violate this Oath, may the reverse be my lot!
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The Hippocratic Oath
(Modern Version)I SWEAR in the presence of the Almighty and before my family, my teachers and my peers that according to my ability and judgment I will keep this Oath and Stipulation.
TO RECKON all who have taught me this art equally dear to me as my parents and in the same spirit and dedication to impart a knowledge of the art of medicine to others. I will continue with diligence to keep abreast of advances in medicine. I will treat without exception all who seek my ministrations, so long as the treatment of others is not compromised thereby, and I will seek the counsel of particularly skilled physicians where indicated for the benefit of my patient.
I WILL FOLLOW that method of treatment which according to my ability and judgment, I consider for the benefit of my patient and abstain from whatever is harmful or mischievous. I will neither prescribe nor administer a lethal dose of medicine to any patient even if asked nor counsel any such thing nor perform the utmost respect for every human life from fertilization to natural death and reject abortion that deliberately takes a unique human life.
WITH PURITY, HOLINESS AND BENEFICENCE I will pass my life and practice my art. Except for the prudent correction of an imminent danger, I will neither treat any patient nor carry out any research on any human being without the valid informed consent of the subject or the appropriate legal protector thereof, understanding that research must have as its purpose the furtherance of the health of that individual. Into whatever patient setting I enter, I will go for the benefit of the sick and will abstain from every voluntary act of mischief or corruption and further from the seduction of any patient.
WHATEVER IN CONNECTION with my professional practice or not in connection with it I may see or hear in the lives of my patients which ought not be spoken abroad, I will not divulge, reckoning that all such should be kept secret.
WHILE I CONTINUE to keep this Oath unviolated may it be granted to me to enjoy life and the practice of the art and science of medicine with the blessing of the Almighty and respected by my peers and society, but should I trespass and violate this Oath, may the reverse by my lot.
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Biol Res. 2010;43(4):429-37---Authors: Votto AP, Domingues BS, de Souza MM, da Silva Júnior FM, Caldas SS, Filgueira DM, Clementin RM, Primel EG, Vallochi AL, Furlong EB, Trindade GS
Abstract--Onion (Allium cepa) is being studied as a potential anticancer agent, but little is known regarding its effect in multidrug resistance (MDR) cells. In this work, the cytotoxicity of crude onion extract (OE) and fractioned extract (aqueous, methanolic and ethyl acetate), as well as some onion compounds (quercetin and propyl disulfide) were evaluated in Lucena MDR human erythroleukemic and its K562 parental cell line. The capacity of OE to induce apoptosis and/or necrosis in these cells, the possible participation of oxidative stress and DNA damage were also assessed. Similar sensitivities were obtained for both tumoral cells, however only OE caused significant effects in the cells. In K562 cells, a significant increase of apoptosis was verified while the Lucena cells experienced a significant increase of necrosis. An antioxidant capacity was verified for OE discarding oxidative damage. However, OE provoked similar significant DNA damage in both cell lines. Thus, the OE capacity to overcome the MDR phenotype suggests anti-MDR action of OE.---PMID: 21526269 [PubMed - indexed for MEDLINE]
Recipe---for an Onion Extract
Making an Onion Extract---you can juice an onion and then fuse in alcohol-brandy-or any clear based alcohol ( ethanol )
You can extract in a juice then fuse with vinegar and add alcohol as well—
Bottle these in glass when doing them and date them---serving size –start off with ½ tsp doses several times a day ( 1-5 ) and either increase strength of dose or increase the amount taken throughout the day
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Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types.
Planta Med. 2012 Jan;78(2):115-21---Authors: Yung LY, Lam WS, Ho MK, Hu Y, Ip FC, Pang H, Chin AC, Harley CB, Ip NY, Wong YH
Abstract---Two Chinese herb-derived small molecule telomerase activators, astragaloside IV (AG-IV) and cycloastragenol (CAG), have recently been shown to improve the proliferative response of CD8+ T lymphocytes from HIV-infected patients by upregulating telomerase activity. Here, we examined the signaling mechanism of AG-IV and CAG. Telomerase activity in human embryonic kidney HEK293 fibroblasts was increased upon treatment with increasing concentrations of AG-IV or CAG. Both compounds induced the phosphorylation of extracellular signal-regulated protein kinase (ERK) in a time- and dose-dependent manner in HEK293 cells and HEK-neo keratinocytes. AG-IV and CAG also stimulated ERK phosphorylation in other cell lines of lung, brain, mammary, endothelial, and hematopoietic origins. Use of selective inhibitors and dominant negative mutants revealed the involvement of c-Src, MEK (ERK kinase), and epidermal growth factor receptor in CAG-induced ERK phosphorylation. Our data indicate that AG-IV and CAG may exert their cellular effects through the activation of the Src/MEK/ERK pathway.--PMID: 22083896 [PubMed - indexed for MEDLINE]
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[U1]Not only minority---any family of any ethnic background----this profiling here shows ignorance ---this could be suggested that non minority may have some immunity to this and that would be erroneous ---especially in today’s thinking
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Attacking Biofilms That Cause Chronic Infections
Gates Poisoning Africa With Vaccines
Composition- efficacy, and safety of spinach extracts
Pressurized liquid extraction of flavonoids from spinach
Vitamin E May Lower Liver Cancer Risk
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Attacking Biofilms That Cause Chronic Infections
3-D reconstruction of the bacterial biofilm made by cholera bacteria. Bacterial cells (blue) attach to surfaces with a glue-like protein (green) and cement themselves together with another protein (gray). The bacterial clusters then cover themselves with a protective shell (red) made of proteins and sugar molecules.
ScienceDaily (July 12, 2012) — A clever new imaging technique discovered at the University of California, Berkeley, reveals a possible plan of attack for many bacterial diseases, such as cholera, lung infections in cystic fibrosis patients and even chronic sinusitis, that form biofilms that make them resistant to antibiotics.---By devising a new fluorescent labeling strategy and employing super-resolution light microscopy, the researchers were able to examine the structure of sticky plaques called bacterial biofilms that make these infections so tenacious. They also identified genetic targets for potential drugs that could break up the bacterial community and expose the bugs to the killing power of antibiotics.--"Eventually, we want to make these bugs homeless," said lead researcher Veysel Berk, a postdoctoral fellow in the Department of Physics and the California Institute for Quantitative Biosciences (QB3) at UC Berkeley.---Berk and his co-authors, including Nobel laureate and former UC Berkeley professor Steven Chu, report their findings in the July 13 issue of the journal Science.---"In their natural habitat, 99.9 percent of all bacteria live as a community and attach to surfaces as biofilms; according to the National Institutes of Health, 80 percent of all infections in humans are related to biofilms," Berk said.---The researchers were able to employ new techniques that allowed them to zoom into a street-level view of these biofilms, where they learned "how they grow from a single cell and come together to form rooms and whole buildings," Berk said. "Now, we can come up with a logical approach to discovering how to take down their building, or prevent them from forming the building itself."--Combining super-resolution microscopy with the technique Berk developed, which allows continuous labeling of growing and dividing cells in culture, biologists in many fields will be able to record stop-motion video of "how bacteria build their castles," he said.--"This work has led to new insights into the development of these complex structures and will no doubt pave the way to new approaches to fighting infectious disease and also bacteriological applications in environmental and industrial settings," said Chu, a former UC Berkeley professor of physics and of molecular and cell biology and former director of the Lawrence Berkeley National Laboratory.
Bacteria are not loners---The popular view of bacteria is that they are free-living organisms easily kept in check by antibiotics, Berk said. But scientists now realize that bacteria spend most of their lives in colonies or biofilms, even in the human body. While single bacteria may be susceptible to antibiotics, the films can be 1,000 times more resistant and most can only be removed surgically.---Implants, such as pacemakers, stents and artificial joints, occasionally become infected by bacteria that form biofilms. These biofilm sites periodically shed bacteria -- adventurers, Berk calls them -- which can ignite acute infections and fever. While antibiotics can knock out these free-swimming bacteria and temporally calm down the infection, the biofilm remains untouched. The only permanent solution is removal of the biofilm-coated device and replacement with a new sterilized implant.---A permanent bacterial biofilm in the sinuses can ignite an immune response leading to chronic sinus infections, with symptoms including fever and cold-like symptoms. So far, the most effective treatment is to surgically remove the affected tissue.--Bacteria also form permanent, mostly lifelong, biofilms in the mucus-filled lungs of cystic fibrosis patients and are responsible for the chronic lung infections that lead to early death. Although long-lasting antibiotic treatment helps, it cannot eradicate the infection completely.---To study a biofilm formed by cholera bacteria (Vibrio cholerae), Berk built his own super-resolution microscope in the basement of UC Berkeley's Stanley Hall based on a 2007 design by coauthor Xiaowei Zhuang, Chu's former post-doctoral student who is now a professor at Harvard University. To actually see these cells as they divided to form "castles," Berk devised a new technique called continuous immunostaining that allowed him to track four separate target molecules by means of four separate fluorescent dyes.---He discovered that, over a period of about six hours, a single bacterium laid down a glue to attach itself to a surface, then divided into daughter cells, making certain to cement each daughter to itself before splitting in two. The daughters continued to divide until they formed a cluster -- like a brick and mortar building -- at which point the bacteria secreted a protein that encased the cluster like the shell of a building.---The clusters are separated by microchannels that may allow nutrients in and waste out, Berk said.---"If we can find a drug to get rid of the glue protein, we can move the building as a whole. Or if we can get rid of the cement protein, we can dissolve everything and collapse the building, providing antibiotic access," Berk said. "These can be targets for site-specific, antibiotic medicines in the future."[U1]
Super-resolution microscopy-- painting with light--Berk is a biologist trained in physics and optics with expertise in imaging the structures of proteins: He was part of a team that a few years ago determined the atomic-scale structures of the ribosome, the cellular machine that translates genetic message into a finished protein.----He suspected that powerful new super-resolution light microscopy could reveal the unknown structure of biofilms. Super-resolution microscopy obtains 10 times better resolution than standard light microscopy -- 20 instead of 200 nanometers -- by highlighting only part of the image at a time using photo-switchable probes and compiling thousands of images into a single snapshot. The process is much like painting with light -- shining a flashlight beam on a dark scene while leaving the camera shutter open. Each snapshot may take a few minutes to compile, but for slow cellular growth, that's quick enough to obtain a stop-action movie.--The problem was how to label the cells with fluorescent dyes to continuously monitor their growth and division. Normally, biologists attach primary antibodies to cells, then flood the cells with fluorescent dye attached to a secondary antibody that latches onto the primary. They then flush away the excess dye, shine light on the dyed cells and photograph the fluorescence.---Berk suspected that a critically balanced concentration of fluorescent stain -- low enough to prevent background, but high enough to have efficient staining -- would work just as well and eliminate the need to flush out excess dye for fear it would create a background glow.---"The classical approach is first staining, then destaining, then taking only a single snapshot," Berk said. "We found a way to do staining and keep all the fluorescent probes inside the solution while we do the imaging, so we can continuously monitor everything, starting from a single cell all the way to a mature biofilm. Instead of one snapshot, we are recording a whole movie."--"It was a very simple, cool idea, but everyone thought it was crazy," he said. "Yes, it was crazy, but it worked."----Berk's coauthors are Steven Chu, now with the U.S. Department of Energy; Jan Liphardt, UC Berkeley professor of physics and of molecular and cell biology; Xiaowei Zhuang and Graham T. Dempsey of Harvard; Jiunn C. N. Fong and Fitnat H. Yildiz of UC Santa Cruz; and Omer N. Develioglu of Taksim Research Hospital in Istanbul, Turkey.--Story Source-The above story is reprinted from materials provided by University of California - Berkeley. --Journal Reference-Veysel Berk, Jiunn C. N. Fong, Graham T. Dempsey, Omer N. Develioglu, Xiaowei Zhuang, Jan Liphardt, Fitnat H. Yildiz, Steven Chu. Molecular Architecture and Assembly Principles of Vibrio cholerae Biofilms. Science, 13 July 2012: Vol. 337 no. 6091 pp. 236-239 DOI: 10.1126/science.1222981
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Gates Poisoning Africa With Vaccines
www.nomorefakenews.com
Melinda Gates has just unrolled her new program to reduce population in Africa and South Asia. Speaking at the Family Planning Summit in London, the other half of the Gates-Messiah operation pledged to bring contraception to millions of women and girls in the Third World.---Flying under the radar, however, is the partnership between The Gates Foundation and drug giant, Pfizer, and therein lies the dirty little secret.-The method of choice to prevent births? Injectable Depo-Provera, long known as a highly dangerous drug. It actually carries a black-box warning on its label, stating that severe bone loss is a consequence of its use. It also thins the vaginal lining, and research is ongoing to investigate the possibility that it increases the risk of breast cancer.--Here is the relevant black-box quote: "Women who use Depro-Provera Contraceptive Injection may lose significant bone mineral density. Bone loss is greater with increased duration of use and may not be completely reversible." --Change.org and several other groups are petitioning the US Congress to cut all federal funding for Depo-Provera. Despite cheerful PR about education of women on the benefits of contraception, and the need for informed consent, these programs have a way of turning into something else out in the field, where the needle meets the body.--Depo-Provera also happens to be a drug of choice for the "chemical castration" of male sex offenders. That fact testifies to its powerful impact on the body.---Nobody at the London Family Planning Summit was talking about Depo-Provera and its severe effects. The conference sponsors, the UN Population Fund, the USAID, and The Gates Foundation, are far more interested in population control.---If millions of girls and women in Africa and South Asia are crippled by the Depo-Provera injections, well, that's just collateral damage. Several years from now, we'll no doubt see studies claiming an unexplained epidemic of osteoporosis in the Third World, which will lead to the application of some other highly toxic drug as the treatment of choice.--Pfizer, the maker of Depo-Provera, happens to make such a drug: Fablyn (Lasofoxifene). So far, the FDA has withheld approval, but the EU gave it the green light in 2009. Fablyn has a serious problem. It causes blood clots in veins, which can be life-threatening.----Watch out, Africa. Melinda's coming with Pfizer. You should ask her why she doesn't supply money to clean up contaminated water supplies, install rudimentary sanitation, provide real nutrition, and help restore stolen fertile land to local farmers.---But you see, those actions aren't in line with the elite agenda. They make things better. The agenda is dedicated to Worse.
www.nomorefakenews.com
qjrconsulting@gmail.com
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Composition- efficacy and safety of spinach extracts.
Lomnitski L, Bergman M, Nyska A, Ben-Shaul V, Grossman S.
Source--Bar-Ilan University, Ramat-Gan, Israel.
Abstract--Spinach leaves, containing several active components, including flavonoids, exhibit antioxidative, antiproliferative, and antiinflammatory properties in biological systems. Spinach extracts have been demonstrated to exert numerous beneficial effects, such as chemo- and central nervous system protection and anticancer and antiaging functions. In this review article, we present a compilation of data generated in our laboratories and those of other investigators describing the chemical composition of spinach, its beneficial effects, relative safety information, and its recommended inclusion in the human diet. A powerful, water-soluble, [U2]natural antioxidant mixture (NAO), which specifically inhibits the lipoxygenase enzyme, was isolated from spinach leaves. The antioxidative activity of NAO has been compared to that of other known antioxidants and found to be superior in vitro and in vivo to that of green tea, N-acetylcysteine (NAC), butylated hydroxytoluene (BHT), and vitamin E. NAO has been tested for safety and is well tolerated in several species, such as mouse, rat, and rabbit. NAO has been found to be nonmutagenic and has shown promising anticarcinogenic effects in a few experimental models, such as skin and prostate cancer; it has not shown any target-organ toxicity or side effects. The current review provides epidemiological and preclinical data supporting the efficacy of extracts of spinach and the safety of its consumption.-PMID-14690799 -[PubMed - indexed for MEDLINE]
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Pressurized liquid extraction of flavonoids from spinach.
Source--Department of Food Science, University of Arkansas, 2650 N. Young Ave., Fayetteville, AR 72704, USA. lukeh@uark.edu
Abstract---Pressurized liquid extraction (PLE) using water and a 70:30 mixture of ethanol and water over the temperature range of 5[U3]0 to 190 degrees C was used to extract flavonoids from dried spinach. The total phenolic content, antioxidant capacity, color, and browning indices of the extracts were also evaluated. PLE using a 70:30 mixture of ethanol and water was more effective than water in extracting flavonoids from[U4] spinach. Flavonoids were effectively extracted over the temperature band of 50 to 130 degrees C with water and 50 to 150 degrees C with ethanolic solvent. Levels of total phenolics and ORAC values increased with increasing extraction temperature, indicating that flavonoids were minor contributors to antioxidant capacity at elevated extraction temperatures. Browning of ethanolic extracts correlated highly with ORAC values over the temperature range of 50 to 190 degrees C, and the ORAC values of the large molecular weight fraction (> 1000 Da) increased linearly over the temperature range, indicating that Maillard polymers were the major contributors to antioxidant capacity. The results illustrate that PLE temperatures of < 130 degrees C for water or < 150 degrees C for ethanolic solvent may be used to extract flavonoids, followed by a high temperature (> 170 degrees C) extraction to generate antioxidant-rich moieties.[U5]
Recipe-Measure out some spinach---3 oz then take about 10 oz of fluid( 70 % vodka or clear based ethanol that is drinkable and 30 percent reverse osmosis or distilled water ) add them to a blender or a bottle blender---and proceed to blend this ---if you have a thermometer you can tap it to the side of the blender to see the heat—when it reaches 120 degrees fahr or 50 cel the you can let it extract for about 5 minutes---turn of blender and strain the material---you will have made this spinach extract
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Vitamin E May Lower Liver Cancer Risk
ScienceDaily (July 17, 2012) — High consumption of vitamin E either from diet or vitamin supplements may lower the risk of liver cancer, according to a study published July 17 in the Journal of the National Cancer Institute.---Liver cancer is the third most common cause of cancer mortality in the world, the fifth most common cancer found in men and the seventh most common in women. Approximately 85% of liver cancers occur in developing nations, with 54% in China alone. Some epidemiological studies have been done to examine the relationship between vitamin E intake and liver cancer; however, the results have been inconsistent.---To determine the relationship between vitamin E intake and liver cancer risk, Wei Zhang, MD, MPH., of the Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine and colleagues analyzed data from a total of 132,837 individuals in China who were enrolled in the Shanghai Women's Health Study (SWHS) from 1997-2000 or the Shanghai Men's Health Study (SMHS) from 2002-2006, two population-based cohort studies jointly conducted by the Shanghai Cancer Institute and Vanderbilt University. Using validated food-frequency questionnaires, the researchers conducted in-person interviews to gather data on study participants' dietary habits. They compared liver cancer risk among participants who had high intake of vitamin E with those with low intake.---The analysis included 267 liver cancer patients (118 women and 149 men) who were diagnosed between 2 years after study enrollment and an average of 10.9 (SWHS) or 5.5 (SMHS) years of follow-up. Vitamin E intake from diet and vitamin E supplement use were both associated with a lower risk of liver cancer. This association was consistent among participants with and without self-reported liver disease or a family history of liver cancer. "We found a clear, inverse dose-response relation between vitamin E intake and liver cancer risk," the authors write, noting a small difference between men and women in the risk estimate, which is likely attributable to fewer liver cancer cases having occurred among SMHS participants due to the shorter follow-up period. Overall, the take home message is that, "high intake of vitamin E either from diet or supplements was related to lower risk of liver cancer in middle-aged or older people from China."---Story Source-The above story is reprinted from materials provided by Journal of the National Cancer Institute, via EurekAlert!, a service of
[U1]We can utilize other things that are herbal or supplemental or even armoatherapeutic to achieve this
[U2]Water soluble==Tea or extracting the spinach at a high velocity extractor ( juice macjhine or blender or extruder )
[U3]Here we go we are using temperatures at 50 cel ( 120 degress fahr ) 190 degree cel ( 374 degrees fahr)-using water and a 70:30 mixture of ( ethanol=vodka gin-brandy-whisky etc ) and water ( distilled or reverse osmosis
[U4]So using a mixture of vodka 70 % and water 30 % was more effective then just using water )
[U5]So the hotter it gets the better antioxidant profle with the mixture of alcohol and water and the many different varieties of antioxidants
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Farm to Market- New Device Makes Cleaning Leafy Greens Easy, Economical
Vaccines Backfire- Veterinary Vaccines Found to Combine Into New Infectious Viruses
Reorganizing Brain Could Lead to Improved Treatments for Stroke, Tinnitus
Evaluation of the antiviral activity of a green tea solution as a hand-wash disinfectant
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Woman Pulls Gun To Prevent Smart Meter Installation
Homeowners reject unconstitutional intrusion
A Harris County woman pulled a gun on a CenterPoint Energy worker to prevent the installation of a smart meter in a confrontation that highlights concerns about the devices being used to spy on Americans’ energy use, as well as possible health impacts.----55-year-old Thelma Taormina has signs posted on her front gate warning utility employees not to trespass on her land, as well as another that reads, “No smart meters are to be installed on this property.”---However, that didn’t stop a CenterPoint Energy worker from attempting to replace Taormina’s old electricity meter with a new device that wirelessly beams back information on each home’s energy use to a central hub.--When the worker began physically pushing Taormina out of the way in an effort to install the smart meter, Taormina drew her gun and demanded the worker leave the property .--[U1]“Our constitution allows us not to have that kind of intrusion on our personal privacy,” Taormina told KHOU 11 News. “They’ll be able to tell if you are running your computer, air conditioner, whatever it is.” --Indeed, privacy experts have warned that smart meters could be used to spy on consumers in a myriad of different ways, including “what appliances are being used in individual homes, and even what programmes are being watched on TV.”---The European Data Protection Supervisor (EDPS) warns that the rollout of smart meters will allow “massive collection of personal data” by utility companies and governments, tracking what “households do within the privacy of their own homes, whether they are away on holiday or at work, if someone uses a specific medical device or a baby monitor, or how they spend their free time”.[U2]--Taormina and her husband also expressed fears about the potential health impacts of the smart meter---The American Academy of Environmental Medicine and other health bodies have voiced concern about potential damaging effects of radio waves emitted by the smart meters and have have urged a moratorium on installing the devices.---The group recently warned that people suffering from “neurological, neurodegenerative diseases, genetic defects, cancer, and other conditions,” should avoid smart meters because they could be “adversely impacted by electromagnetic frequency (EMF) and radiofrequency (RF) fields,” emitted by the devices.[U3]--The Public Utilities Commission is now debating whether to allow homeowners who have already had smart meters installed to have them removed. In other areas of the country, utility companies are forcing residents to pay an extra charge to stay on conventional analogue meters.---CenterPoint Energy is now threatening to take Taormina to court over her actions in forcing the utility worker off her property.
http://www.infowars.com/woman-pulls-gun-to-prevent-smart-meter-installation/
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Farm to Market- New Device Makes Cleaning Leafy Greens Easy, Economical
A simple and inexpensive device to wash leafy produce, created by students at the University of Houston Conrad N. Hilton College of Hotel and Restaurant Management (HRM), may provide a convenient way for small farmers to clean produce before market. (Credit: Image courtesy of University of Houston)---ScienceDaily (July 16, 2012) — A simple and inexpensive device to wash leafy produce, created by students at the University of Houston Conrad N. Hilton College of Hotel and Restaurant Management (HRM), may provide a convenient way for small farmers to clean produce before market.---"Leafy greens have the highest incidence of contamination nationwide," said graduate student Cecilia Zerio Egli. "There is not a lot of research available for smaller farms to access methods for efficiently and economically washing produce before it goes to markets."---Zerio Egli is studying in the HRM Food Safety Laboratory, directed by Professor Jay Neal. The laboratory performs microbiological and sensory research, while collaborating and publishing with other universities and government agencies. In addition, the lab has a full production kitchen, as well as a sensory evaluation laboratory. In August 2012, the lab will achieve a Bio-Safety Level 2 upgrade, which will enable researchers to work with pathogenic or disease causing microorganisms.---Supported by a grant from the Texas Department of Agriculture, Zerio Egli and Neal surveyed more than 80 local and regional farmers about their harvesting and washing practices, asking if they would use a washing device if it were available. "Small famers" were defined as earning less than $500,000 annually. These farms are exempt from the Food and Drug Administration's Food Safety Modernization Act, which focuses on preventing food contamination rather than responding to outbreaks.---Unlike large commercial farms that can ship produce to packing facilities that wash the vegetables, smaller farmers must do everything themselves, from harvesting and packaging to transporting to market. Not all produce is washed before heading to market.---"Packing sheds have flumes which are water-wash systems with a chlorinated treatment," Neal said. "When you buy packaged lettuce that says 'washed three times' that's how it was done. Small famers don't have that."-Zerio Egli's device is made from PVC pipe, a stainless steel strainer and a five-gallon drum. Leafy vegetables placed inside the stainless steel container are spun as they're showered briefly with water to remove dirt. With the flick of a lever, the container lowers into the plastic drum where it is spun in a vinegar and water solution, proven to best clean produce of any harmful bacteria. Finally, the container is lifted to its original position where the produce is rinsed with water again.---I'll be making an information sheet which will have the plans for how small farmers can easily build the device themselves and where they can purchase the inexpensive materials," she said. "And farmers can manipulate the size to fit their individual needs." The information sheet also will have resources for farmers about best practices when growing, harvesting and washing produce.--Zerio Egli and Neal plan to make the plans available in the fall to farmers and --Story Source-The above story is reprinted from materials provided by University of Houston.
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Vaccines Backfire- Veterinary Vaccines Found to Combine Into New Infectious Viruses
Vaccines combine to produce new virus strain. ---ScienceDaily (July 12, 2012) — Research from the University of Melbourne has shown that two different vaccine viruses- used simultaneously to control the same condition in chickens- have combined to produce new infectious viruses, prompting early response from Australia's veterinary medicines regulator.---The vaccines were used to control infectious laryngotracheitis (ILT), an acute respiratory disease occurring in chickens worldwide. ILT can have up to 20% mortality rate in some flocks and has a significant economic and welfare impact in the poultry industry.--The research found that when two different ILT vaccine strains were used in the same populations, they combined into two new strains (a process known as recombination), resulting in disease outbreaks.---Neither the ILT virus or the new strains can be transmitted to humans or other animals, and do not pose a food safety risk.---The study was led by Dr Joanne Devlin, Professor Glenn Browning and Dr Sang-Won Lee and colleagues at the Asia-Pacific Centre for Animal Health at the University of Melbourne and NICTA's Victoria Research Laboratory and is published July 13, 2012] in the journal Science.--Dr Devlin said the combining of live vaccine virus strains outside of the laboratory was previously thought to be highly unlikely, but this study shows that it is possible and has led to disease outbreaks in poultry flocks.--"We alerted the Australian Pesticide and Veterinary Medicines Authority (APVMA) to our findings and they are now working closely with our research team, vaccine registrants and the poultry industry to determine both short and long term regulatory actions," she said.---"Short-term measures include risk assessment of all live virus vaccines currently registered by the APVMA in regard to the risk of recombination and could include changes to product labels, which may result in restrictions on the use of two vaccines of different origins in the one animal population."---The ILT vaccines are 'live attenuated vaccines', which means that the virus has some disease-causing factors removed but the immune system still recognises the virus to defend against a real infection.---"Live vaccines are used throughout the world to control ILT in poultry. For over 40 years the vaccines used in Australia were derived from an Australian virus strain. But following a vaccine shortage another vaccine originating from Europe was registered in 2006 and rapidly became widely used,"[U4] Dr Devlin said.---"Shortly after the introduction of the European strain of vaccine, two new strains of ILT virus were found to be responsible for most of the outbreaks of disease in New South Wales and Victoria. So we sought to examine the origin of these two new strains."---The team sequenced all of the genes (the genome) of the two vaccines used in Australia, and the two new outbreak strains of the virus. Following bioinformatic analysis on the resulting DNA sequence, in conjunction with Dr John Markham at NICTA's Victoria Research Laboratory, they found that the new disease-causing strains were combinations of the Australian and European origin vaccine strains.---[U5]"Comparisons of the vaccine strains and the new recombinant strains have shown that both the recombinant strains cause more severe disease, or replicate to a higher level than the parent vaccine strains that gave rise to them," Dr Lee said.---Professor Glenn Browning said recombination was a natural process that can occur when two viruses infect the same cell at the same time.---"While recombination has been recognised as a potential risk associated with live virus vaccines for many years, the likelihood of it happening in viruses like this in the field has been thought to be so low that it was considered to be very unlikely to lead to significant problems," he said.--"Our studies have shown that the risk of recombination between different vaccine strains in the field is significant as two different recombinant viruses arose within a year. We also demonstrated that the consequences of such recombination can be very severe, as the new viruses have been responsible for the deaths of thousands of Australian poultry."---"The study suggests that regulation of live attenuated vaccines for all species needs to take into account the real potential for vaccine viruses to combine. Measures such as those now being taken for the ILT vaccines will need to be implemented."-The above story is reprinted from materials provided by University of Melbourne, via EurekAlert!, a service of AAAS. --Journal Reference-Sang-Won Lee, Philip F. Markham, Mauricio J. C. Coppo, Alistair R. Legione, John F. Markham, Amir H. Noormohammadi, Glenn F. Browning, Nino Ficorilli, Carol A. Hartley, and Joanne M. Devlin. Attenuated Vaccines Can Recombine to Form Virulent Field Viruses. Science, 13 July 2012: 188 DOI: 10.1126/science.1217134
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Reorganizing Brain Could Lead to Improved Treatments for Stroke, Tinnitus
ScienceDaily (July 19, 2012) — UT Dallas researchers recently demonstrated how nerve stimulation paired with specific experiences, such as movements or sounds, can reorganize the brain. This technology could lead to new treatments for stroke, tinnitus, autism and other disorders.---In a related paper, UT Dallas neuroscientists showed that they could alter the speed at which the brain works in laboratory animals by pairing stimulation of the vagus nerve with fast or slow sounds.--A team led by Dr. Robert Rennaker and Dr. Michael Kilgard looked at whether repeatedly pairing vagus nerve stimulation with a specific movement would change neural activity within the laboratory rats' primary motor cortex. To test the hypothesis, they paired the vagus nerve stimulation with movements of the forelimb in two groups of rats. The results were published in a recent issue of Cerebral Cortex.--After five days of stimulation and movement pairing, the researchers examined the brain activity in response to the stimulation. The rats who received the training along with the stimulation displayed large changes in the organization of the brain's movement control system. The animals receiving identical motor training without stimulation pairing did not exhibit any brain changes, or plasticity.--People who suffer strokes or brain trauma often undergo rehabilitation that includes repeated movement of the affected limb in an effort to regain motor skills. It is believed that repeated use of the affected limb causes reorganization of the brain essential to recovery. The recent study suggests that pairing vagus nerve stimulation with standard therapy may result in more rapid and extensive reorganization of the brain, offering the potential for speeding and improving recovery following stroke, said Rennaker, associate professor in The University of Texas at Dallas' School of Behavioral and Brain Sciences---"Our goal is to use the brain's natural neuromodulatory systems to enhance the effectiveness of standard therapies," Rennaker said. "Our studies in sensory and motor cortex suggest that the technique has the potential to enhance treatments for neurological conditions ranging from chronic pain to motor disorders. Future studies will investigate its effectiveness in treating cognitive impairments."---Since vagus nerve stimulation has an excellent safety record in human patients with epilepsy, the technique provides a new method to treat brain conditions in which the timing of brain responses is abnormal, including dyslexia and schizophrenia.---In another paper in the journal Experimental Neurology, Kilgard led a team that paired vagus nerve stimulation with audio tones of varying speeds to alter the rate of activity within the rats' brains. The team reported that this technique induced neural plasticity within the auditory cortex, which controls hearing.---The UT Dallas researchers are working with a device developed by MicroTransponder, a biotechnology firm affiliated with the University. MicroTransponder currently is testing a vagus nerve stimulation therapy on human patients in Europe in hopes of reducing or eliminating the symptoms of tinnitus, the debilitating disorder often described as "ringing in the ears."---"Understanding how brain networks self-organize themselves is vitally important to developing new ways to rehabilitate patients diagnosed with autism, dyslexia, stroke, schizophrenia and Alzheimer's disease," said Kilgard, a professor of neuroscience.---Treatment of neurological disease is currently limited to pharmacological, surgical or behavioral interventions. But this recent research indicates it may be possible to effectively manipulate the plasticity of the human brain for a variety of purposes[U6]. Patients then could benefit from brain activity intentionally directed toward rebuilding lost skills.--If subsequent studies confirm the UT Dallas findings, human patients may have access to more efficient therapies that are minimally invasive and avoid long-term use of drugs.---Story Source-The above story is reprinted from materials provided by University of Texas at Dallas. --Journal References-Porter BA, Khodaparast N, Fayyaz T, Cheung RJ, Ahmed SS, Vrana WA, Rennaker RL 2nd, Kilgard MP. Repeatedly Pairing Vagus Nerve Stimulation with a Movement Reorganizes Primary Motor Cortex. Cereb Cortex, 2011 Nov 10 [link]---Shetake JA, Engineer ND, Vrana WA, Wolf JT, Kilgard MP. Pairing tone trains with vagus nerve stimulation induces temporal plasticity in auditory cortex. Exp Neurol., 2012 Jan [link]
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Evaluation of the antiviral activity of a green tea solution as a hand-wash disinfectant.
Biosci Biotechnol Biochem. 2012;76(3):581-4--Authors: Shin WJ, Kim YK, Lee KH, Seong BL
Abstract--Based on the broad-spectrum antiviral effect of green tea catechins, we established an experimental skin contact model for influenza virus transmission and evaluated the use of a green tea solution as a first-hand disinfectant. The infectivity of the virus on the skin cell layer became obsolete when washed with the green tea solution. The skin contact model could be applied to develop non-pharmaceutical intervention measures for reducing human transmission of the influenza virus.
Recipe---take green tea and extract it in a alcohol material( vodka-grapp-gin-etc) Put in you blender and extract the green tea by blending the 2 for 10 minutes---utilize a 2:1 ratio of alcohol to the green tea( you can go one to one if you choose or any level you deem fit) if you wish to add water with the alcohol then ad 1 part to the 2 parts of alcohol---once blended for the time frame then strain and filter out the material and added to a castile soap and you have made yourself a antiviral solution with green tea
[U1]Here is a woman I admire---she has some brass tacks and stood her ground---now I am wondering if more will follow !!!
[U2]This can allow for unlawful entry by the police or anyone working on staff can now have access to this information and while you’re a way on a holiday or vacation they can break in your place and rob you blind
[U3]Unsafe Monitoring devises that further destroy your health and further debilitate you
[U4]Potential Sabotage???
[U5]Possible Sabotage!!?
[U6]This is a bit of an alarming statement here—what if I take the frequency of these sounds and placed them in a audio device and hit those notes or sounds could this re wire the brain in another way??since this is a programming device –what os to stop this from becoming a rewiring a bit of hardware –our brains?
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Powerful Class of Antioxidants May Be Potent Parkinson's Treatment
Smart Meters- Correcting the Gross Misinformation
How Malnutrition Leads to Inflamed Intestines
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Chemical compound: Common Name (Latin Name)
- 20-hydroxyecdysone: maral root (Rhaponticum carthamoides)
- araloside: spikenard (Aralia mandshurica)
- astragaloside: huang qi (Astragalus membranaceus)
- bacoside: brahmi (Bacopa monniera)
- cucurbitacin: bryonia (Bryonia alba)
- eleutheroside: Siberian ginseng (Eleutherococcus senticosus)
- ginsenoside: ginseng (Panax ginseng)
- gymnemic acid: gurmar (Gymnema sylvestre)
- gypenoside: jiaogulan (Gynostemma pentaphyllum)
- tanshenoside: bellflower (Codonopsis pilosula)
- tinosporoside: guruchi (Tinospora cordifolia)
- withanolide: ashwagandha (Withania somnifera)
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Powerful Class of Antioxidants May Be Potent Parkinson's Treatment
ScienceDaily (July 23, 2012) — A new and powerful class of antioxidants could one day be a potent treatment for Parkinson's disease, researchers report.--A class of antioxidants called synthetic triterpenoids blocked development of Parkinson's in an animal model that develops the disease in a handful of days, said Dr. Bobby Thomas, neuroscientist at the Medical College of Georgia at Georgia Health Sciences University and corresponding author of the study in the journal Antioxidants & Redox Signaling.---Thomas and his colleagues were able to block the death of dopamine-producing brain cells that occurs in Parkinson's by using the drugs to bolster Nrf2, a natural antioxidant and inflammation fighter.-----Stressors from head trauma to insecticide exposure to simple aging increase oxidative stress and the body responds with inflammation, part of its natural repair process. "This creates an environment in your brain that is not conducive for normal function," Thomas said. "You can see the signs of oxidative damage in the brain long before the neurons actually degenerate in Parkinson's."--Nrf2, the master regulator of oxidative stress and inflammation, is -- inexplicably -- significantly decreased early in Parkinson's. In fact, Nrf2 activity declines normally with age.--"In Parkinson's patients you can clearly see a significant overload of oxidative stress, which is why we chose this target," Thomas said. "We used drugs to selectively activate Nrf2."--They parsed a number of antioxidants already under study for a wide range of diseases from kidney failure to heart disease and diabetes, and found triterpenoids the most effective on Nrf2. Co-author Dr. Michael Sporn, Professor of Pharmacology, Toxicology and Medicine at Dartmouth Medical School, chemically modified the agents so they could permeate the protective blood-brain barrier.---Both in human neuroblastoma and mouse brain cells they were able to document an increase in Nrf2 in response to the synthetic triterpenoids. Human dopaminergic cells are not available for research so the scientists used the human neuroblastoma cells, which are actually cancer cells that have some properties similar to neurons.--Their preliminary evidence indicates the synthetic triterpenoids also increase Nrf2 activity in astrocytes, a brain cell type which nourishes neurons and hauls off some of their garbage. The drugs didn't protect brain cells in an animal where the Nrf2 gene was deleted, more proof that that Nrf2 is the drugs' target.--The researchers used the powerful neurotoxin MPTP to mimic Parkinson's-like brain cell damage in a matter of days. They are now looking at the impact of synthetic triterpenoids in an animal model genetically programmed to acquire the disease more slowly, as humans do. Collaborators at Johns Hopkins School of Medicine also will be providing induced pluripotent stem cells, adult stem cells that can be coaxed into forming dopaminergic neurons, for additional drug testing.---Other collaborators include scientists at Weill Medical College of Cornell University, Johns Hopkins School of Public Health, Moscow State University, Tohoku University and the University of Pittsburgh.--Story Source-The above story is reprinted from materials provided by Georgia Health Sciences University. --Journal Reference-Navneet Ammal Kaidery, Rebecca Banerjee, Lichuan Yang, Natalya A Smirnova, Dmitry M Hushpulian, Karen T Liby, Charlotte W Williams, Masayuki Yamamoto, Thomas W. Kensler, RAJIV RATAN, Michael B Sporn, Flint Beal, Irina G Gazaryan, Bobby Thomas. Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP- mouse model of Parkinson’s disease. Antioxidants & Redox Signaling, 2012; : 120701083204005 DOI: 10.1089/ars.2011.4491
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Smart Meters- Correcting the Gross Misinformation
http://www.youtube.com/watch?v=sKoiFJFRy0M&feature=player_embedded#!
http://www.youtube.com/watch?v=2pcGAv4rTko&feature=player_embedded#!
Quebec-based magazine La Maison du 21e siecle asked physician David O. Carpenter, former founding dean of the University at Albany (NY)’s School of Public Health, to comment on a letter published in the Montreal daily Le Devoir last May 24. This letter claimed wireless smart meters pose no risk to public health. Some fourty international experts contributed to the following rebuttal.
We, the undersigned are a group of scientists and health professionals who together have coauthored hundreds of peer-reviewed studies on the health effects of electromagnetic fields (EMFs). We wish to correct some of the gross misinformation found in the letter regarding wireless “smart” meters that was published in the Montreal daily Le Devoir on May 24. Submitted by a group Quebec engineers, physicists and chemists, the letter in question reflects an obvious lack of understanding of the science behind the health impacts of the radio frequency (RF)/microwave EMFs emitted by these meters.---The statement that « Thousands of studies, both epidemiological and experimental in humans, show no increase in cancer cases as a result of exposure to radio waves of low intensity… » is false (1). In fact, only a few such studies — two dozen case-control studies of mobile phone use, certainly not thousands, have reported no elevations of cancer, and most were funded by the wireless industry. In addition, these reassuring studies contained significant experimental design flaws, mainly the fact that the populations followed were too small and were followed for a too short period of time.---Non industry-funded studies have clearly demonstrated a significant increase in cancer cases among individuals who have suffered from prolonged exposure to low-level microwaves, transmitted notably by radio antennas. The effects were best documented in meta-analyses that have been published and that include grouped results from several different studies: these analyses consistently showed an increased risk of brain cancer among regular users of a cell phone who have been exposed to microwaves for at least ten years.
Brain Cancer Rates-------Furthermore, the argument that brain cancer rates do not indicate an overall increase in incidence is not evidence that cell phones are safe: the latency for brain cancer in adults after environmental exposure can be long, up to 20-30 years. Most North Americans haven’t used cell phones extensively for that long. The evidence of the link between long-term cell phone use and brain cancer comes primarily from Northern Europe, where cell phones have been commonly used since the 1990s.--------Children are especially at risk. In May 2012, the U.K.’s Office of National Statistics reported a 50 percent increase in incidence of frontal and temporal lobe tumors in children between 1999 and 2009. This statistic is especially disturbing since in May 2011, after reviewing the published scientific literature regarding cancers affecting cell phone users, the International Agency for Research on Cancer (IARC) classified radiofrequency radiation as a 2B, possible human carcinogen. Despite the absence of scientific consensus, the evidence is sufficiently compelling for any cautious parent to want to reduce their loved one’s exposure to RF/microwave emissions as much as possible, as recommended by various countries such as Austria, Belgium, Germany,Russia and the United Kingdom.
Electrosensitivity---Public fears about wireless smart meters are well-founded. They are backed by various medical authorities such as those of the Santa Cruz County(California) Public Health Department. These authorities are worried about the growing number of citizens who say they have developed electro hypersensitivity (EHS), especially since for many of them, the symptoms developed after the installation of such meters (it takes some time for most people to link the two events).--Since the turn of the millennium, people are increasingly affected by ambient microwaves due to the growing popularity of wireless devices such as cell phones and Wi-Fi Internet. Therefore, the mass deployment of smart grids could expose large chunks of the general population to alarming risk scenarios without their consent. According to seven surveys done in six European countries between 2002 and 2004, about 10% of Europeans have become electrosensitive, and experts fear that percentage could reach 50% by 2017. The most famous person to publicly reveal her electrosensitivity is Gro Harlem Brundtland, formerly Prime Minister of Norway and retired Director of the World Health Organization (WHO).----While there is no consensus on the origins and mechanisms of EHS, many physicians and other specialists around the world have become aware that EHS symptoms (neurological dermatological, acoustical, etc.) seem to be triggered by exposure to EMF levels well below current international exposure limits, which are established solely on short-term thermal effects (2). Organizations such as the Austrian Medical Associationand the American Academy of Environmental Medicine have recognized that the ideal way to treat of EHS is to reduce EMF exposure.--------Therefore, caution is warranted because the growing variety of RF/microwave emissions produced by many wireless devices such as smart meters have never been tested for their potential biological effects.
Well-known bioeffects
While the specific pathways to cancer are not fully understood, it is scientifically unacceptable to deny the weight of the evidence regarding the increase in cancer cases in humans that are exposed to high levels of RF/microwave radiation.---The statement that « there is no established mechanism by which a radio wave could induce an adverse effect on human tissue other than by heating » is incorrect, and reflects a lack of awareness and understanding of the scientific literature on the subject. In fact, more than a thousand studies done on low intensity, high frequency, non-ionizing radiation, going back at least fifty years, show that some biological mechanisms of effect do not involve heat. This radiation sends signals to living tissue that stimulate biochemical changes, which can generate various symptoms and may lead to diseases such as cancer.----Even though RF/microwaves don’t have the energy to directly break chemical bonds, unlike ionizing radiation such as X-rays, there is scientific evidence that this energy can cause DNA damage indirectly leading to cancer by a combination of biological effects[U1]. Recent publications have documented the generation of free radicals, increased permeability of the blood brain barrier allowing potentially toxic chemicals to enter the brain, induction of genes, as well as altered electrical and metabolic activity in human brains upon application of cell phone RF/microwaves similar to those produced by smart meters.---These effects are cumulative and depend on many factors including RF/microwave levels, frequency, waveform, exposure time, biovariability between individuals and combination with other toxic agents[U2]. Clear evidence that these microwaves are indeed bioactive has been shown by the fact that low-intensity EMFs have proven clinically useful in some circumstances. Pulsed EMFs have long been used to successfully treat bone fractures that are resistant to other forms of therapy. More recently, frequency-specific, amplitude-modulated EMFs have been found useful to treat advanced carcinoma and chronic pain.----High frequency EMFs such as the microwaves used in cell phones, smart meters, Wi-Fi and cordless ‘‘DECT’’ phones, appear to be the most damaging when used commonly. Most of their biological effects, including symptoms of electrohypersensitivity, can be seen in the damage done to cellular membranes by the loss of structurally-important calcium ions. Prolonged exposure to these high frequencies may eventually lead to cellular malfunction and death.----Furthermore, malfunction of the parathyroid gland, located in the neck just inches from where one holds a cell phone, may actually cause electrohypersensitivity in some people by reducing the background level of calcium ions in the blood. RF/microwave radiation is also known to decrease the production of melatonin, which protects against cancer, and to promote the growth of existing cancer cells.Early warning scientists attacked----In recommending that the Precautionary Principle be applied in EMF matters, the European Environment Agency’s Director Jacqueline McGlade wrote in 2009: “We have noted from previous health hazard histories such as that of lead in petrol, and methyl mercury, that ‘early warning’ scientists frequently suffer from discrimination, from loss of research funds, and from unduly personal attacks on their scientific integrity. It would be surprising if this is not already a feature of the present EMF controversy… » Such unfortunate consequences have indeed occurred.---The statement in the Le Devoir letter that « if we consider that a debate should take place, it should focus exclusively on the effects of cell phones on health » is basically an acknowledgement that there is at least some reason to be concerned about cell phones. However, while the immediate exposure from a cell phone is of much greater intensity than the exposure from smart meters, cell phone use is temporary.
Smart meters---Wireless smart meters typically produce atypical, relatively potent and very short pulsed RF/microwaves whose biological effects have never been fully tested. They emit these millisecond-long RF bursts on average 9,600 times a day with a maximum of 190,000 daily transmissions and a peak level emission two and a half times higher than the stated safety signal, as the California utility Pacific Gas & Electric recognized before that State’s Public Utilities Commission. Thus people in proximity to a smart meter are at risk of significantly greater aggregate exposure than with a cell phone, not to mention the cumulative levels of RF/microwaves that people living near several meters are exposed to.------People are exposed to cell phone microwaves primarily in the head and neck, and only when they use their device. With smart meters, the entire body is exposed to the microwaves, which increases the risk of overexposure to many organs.---In addition to these erratic bursts of modulated microwaves coming from smart meters that are transferring usage data to electric, gas and water utilities, wireless and wired smart (powerline communication) meters are also a major source of ‘’dirty electricity’’ (electrical interference of high frequency voltage transients typically of kilohertz frequencies). Indeed, some scientists, such as American epidemiologist Sam Milham, believe that many of the health complaints about smart meters may also be caused by dirty electricity generated by the « switching » power supply activating all smart meters. Since the installation of filters to reduce dirty electricity circulating on house wiring has been found to relieve symptoms of EHS in some people, this method should be considered among the priorities aimed at reducing potential adverse impacts. Indeed, the Salzburg State (Austria) Public Health Department confirms its concern about the potential public health risk when in coming years almost every electric wire and device will emit such transient electric fields in the kilohertz-range due to wired smart meters.
Rather be safe than sorry---The apparent adverse health effects noted with smart meter exposure are likely to be further exacerbated if smart appliances that use wireless communications become the norm and further increase unwarranted exposure.---To date, there have been few independent studies of the health effects of such sources of more continuous but lower intensity microwaves. However, we know after decades of studies of hazardous chemical substances, that chronic exposure to low concentrations of microwaves can cause equal or even greater harm than an acute exposure to high concentrations of the same microwaves.--This is why so many scientists and medical experts urgently recommend that measures following the Precautionary Principle be applied immediately — such as using wired meters — to reduce biologically inappropriate microwave exposure. We are not advocating the abolishment of RF technologies, only the use of common sense and the development and implementation of best practices in using these technologies in order to reduce exposure and risk of health hazards.
1. Scientific papers on EMF health effects
2. Explanation and studies on electrosensitivity
3. Governments and organizations that ban or warn against wireless technology• David O. Carpenter, MD, Director, Institute for Health & the Environment, University at Albany, USA
• Jennifer Armstrong, MD, Past President, Canadian Society of Environmental Medicine, Founder, Ottawa Environmental Health Clinic, Ontario, Canada
• Pierre L. Auger, M. D., FRCPC, Occupational medicine, Multiclinique des accidentés 1464, Montreal, Quebec, Canada
• Fiorella Belpoggi, Director Cesare Maltoni Cancer Research Center, Ramazzini Institute, Bologna, Italy
• Martin Blank, PhD, former President, Bioelectromagnetics Society, Special Lecturer, Department of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, USA
• Barry Breger, MD, Centre d’intégration somatosophique (orthomolecular medicine), Montreal, Quebec
• John Cline, MD, Professor, Institute for Functional Medicine, Federal Way, WA, USA, Medical Director, Cline Medical Centre, Nanaimo, BC, Canada
• Alvaro Augusto de Salles, PhD, Professor of Electrical Engineering, Federal University of Rio Grande do Sul, Porto Alegre, Brazil
• Christos Georgiou, Prof. Biochemistry, Biology Department, University of Patras, Greece
• Andrew Goldsworthy, PhD, Honorary lecturer in Biology, Imperial College, London, UK
• Claudio Gómez-Perretta, MD, PhD, Director, Centro de Investigación, Hospital Universitario LA Fe, Valencia, Spain
• Livio Giuliani, PhD, Senior Researcher, National Insurance Institute (INAIL), Chief of Radiation and Ultrasounds Research Unit, Rome, Italy
• Yury Grigoriev, PhD, Chair Russian National Committee on Non-Ionizing Radiation Protection, Moscow, Russia
• Settimio Grimaldi, PhD, Director, Institute of Translational Pharmacology (Neurobiology and molecular medicine), National Research Council, Rome, Italy
• Magda Havas, PhD, Centre for Health Studies, Trent University, Canada
• Lennart Hardell, MD, Professor of Oncology, University Hospital, Örebro, Sweden
• Denis L. Henshaw, PhD, Professor of Physics, Head of The Human Radiation Effects Group, University of Bristol, UK
• Ronald B. Herberman, MD, Chairman of Board, Environmental Health Trust, and Founding Director emeritus, University of Pittsburgh Cancer Institute, USA
• Isaac Jamieson, PhD Environmental Science (electromagnetic phenomena in the built environment), independent architect, scientist and environmental consultant, Hertfordshire, UK
• Olle Johansson, PhD, Professor of Neuroscience (Experimental Dermatology Unit), Karolinska Institute, Stockholm, Sweden
• Yury Kronn, PhD, Soviet authority on physics of nonlinear vibrations and high frequency electromagnetic vibrations, founder of Energy Tools International, Oregon, USA
• Henry Lai, PhD, Professor of Bioengineering, University of Washington School of Medicine, Seattle, WA, USA
• Abraham R. Liboff, PhD, Professor Emeritus, Department of Physics, Oakland University, Rochester, Michigan, USA
• Don Maisch, PhD, Researcher on radiation exposure standards for telecommunications frequency, EMFacts Consultancy, Tasmania, Australia
• Andrew A. Marino, MD, PhD, JD, Professor of Neurology, LSU Health Sciences Center, Shreveport, LA, USA
• Karl Maret, MD, M.Eng., President, Dove Health Alliance, Aptos, CA, USA
• Sam Milham, MD, former chief epidemiologist, Washington State Department of Health, USA
• Joel M. Moskowitz, PhD, Director, Center for Family and Community Health, School of Public Health, University of California, Berkeley
• Gerd Oberfeld, MD, Public Health Department, Salzburg State Government, Austria
• Jerry L. Phillips, PhD, Director, Center for Excellence in Science, Department of Chemistry and Biochemistry, University of Colorado, USA
• John Podd, PhD, Professor of Psychology (experimental neuropsychology), Massey University, New-Zeland
• William J. Rea, MD, thoracic and cardiovascular surgeon, founder of the Environmental Health Center, Dallas, Tx, USA
• Elihu D. Richter, MD, Professor, Hebrew University-Hadassah School of Public Health and Community Medicine, Jerusalem, Israel
• Leif G. Salford, MD, Senior Professor of Neurosurgery, Lund University, Sweden
• Nesrin Seyhan, MD, Founder and Chair of Biophysics, Medical Faculty of Gazi University, Turkey
• Cyril W. Smith, PhD, lead author of “Electromagnetic Man”, retired from Electronic and Electrical Engineering, University of Salford, UK
• Morando Soffritti, MD, Scientific Director of the European Foundation for Oncology and Environmental Sciences “B. Ramazzini” in Bologna, Italy
• Antoinette “Toni” Stein, PhD, Collaborative on Health and the Environment (CHE-EMF Working Group), Co-Coordinator, Berkeley, CA, USA
• Stanislaw Szmigielski, MD, PhD Professor of Pathophysiology, Consulting Expert, former director of Microwave Safety, Military Institute of Hygiene and Epidemiology, Warsaw, Poland
• Bradford S. Weeks, MD, Director, The Weeks Clinic, Clinton, WA, USA
• Stelios A. Zinelis, MD, Vice-President, Hellenic Cancer Society, Cefallonia, GreeceSource- -http://maisonsaine.ca/smart-meters-correcting-the-gross-misinformation/
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How Malnutrition Leads to Inflamed Intestines
Malnutrition--ScienceDaily (July 24, 2012) — More than one billion people in poor countries are starving, and malnutrition remains a major problem even in rich countries, making it a leading cause of death in the world. For over a hundred years, doctors have known that a lack of protein in the diet or low levels of amino acids, the building blocks of proteins, can lead to symptoms like diarrhoea, inflamed intestines and other immune system disorders, which weaken the body and can be fatal. However, the molecular mechanism which explains how malnutrition causes such severe symptoms has been largely unexplored.--Now a research group led by Josef Penninger, the director of the Institute of Molecular Biotechnology (IMBA) in Vienna, Austria, in cooperation with Philip Rosenstiel, University of Kiel, Germany, has found a molecular explanation for the increased susceptibility to intestinal inflammation in malnutrition. The researchers were studying an enzyme which helps to control blood pressure, kidney failure in diabetes, heart failure and lung injury, called the Angiotensin Converting Enzyme 2, or ACE2. This enzyme was identified as the key receptor for SARS virus infections, but the researchers also discovered an entirely new function. ACE2 controls the way our intestines take in amino acids from our food, via amino acid transporters, and in particular the uptake of the essential amino acid tryptophan.----Too little tryptophan alters our natural immune system, which changes the types of bacteria which can live in our bowels and guts, leading to higher sensitivity and eventually diarrhoea and inflamed intestines. Increasing the intake of tryptophan in their diet provided relief for mice suffering from intestinal inflammation. The mixture of bacteria returned to normal, the inflammation died down, and the mice also became less susceptible to new attacks.--"The research shows how the food we eat can directly change the good bacteria in our intestines to bad bacteria and so influence our health”, says Thomas Perlot, the first author of the study. “Our results might also explain nutritional effects that have been known for centuries and provide a molecular link between malnutrition and the bacteria living in our intestines. This discovery could be used in the future to treat patients with a simple regulated diet or by taking tryptophan as a food supplement. And there is hardly any risk of side effects from artificially increasing an amino acid found in the normal diet.”---Josef Penninger, the lead author, says “I have studied ACE2 for more than 10 years and was completely stunned by this novel link between ACE2 and amino acid balance in the gut. Biology continues to surprise me. Up to a billion people in the world are malnourished, especially the poor and disadvantaged. In Austria alone, around 80,000 people suffer from a chronic inflammatory bowel disease like ulcerative colitis or Crohn's disease. I hope that our findings have opened a door to a better molecular understanding how malnutrition affects human health. Whether simple tryptophan diets can indeed cure the effects of malnutrition in humans now needs to be carefully tested in clinical trials.”
Story Source-The above story is reprinted from materials provided by Institute of Molecular Biotechnology, via AlphaGalileo.
Journal Reference-Tatsuo Hashimoto, Thomas Perlot, Ateequr Rehman, Jean Trichereau, Hiroaki Ishiguro, Magdalena Paolino, Verena Sigl, Toshikatsu Hanada, Reiko Hanada, Simone Lipinski, Birgit Wild, Simone M. R. Camargo, Dustin Singer, Andreas Richter, Keiji Kuba, Akiyoshi Fukamizu, Stefan Schreiber, Hans Clevers, Francois Verrey, Philip Rosenstiel, Josef M. Penninger. ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature, 2012; 487 (7408): 477 DOI: 10.1038/nature11228
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[U1]A combination of Bio effects---lets just say Chemtrail Particulates loaded with 23 components—then add mercury leaking lights from cfl’s and what do you have---a combination of radiation and metals toxic to human life
[U2]Again between Individual and combination of toxic agents---this is a wholesale set up to sell us technology to increase a causative effect on deblaitating people and inflctions of radiation and metal poisonings that can effect the brain
